TY - JOUR
T1 - Presenting manifestations of hemophagocytic syndrome in a male patient with systemic lupus erythematosus
AU - Taki, Hirofumi
AU - Shinoda, Koichiro
AU - Hounoki, Hiroyuki
AU - Ogawa, Reina
AU - Hayashi, Ryuji
AU - Sugiyama, Eiji
AU - Tobe, Kazuyuki
PY - 2010/1
Y1 - 2010/1
N2 - Hemophagocytic syndrome (HPS) is an unusual but sometimes fatal disorder. We reported a case of 21-year-old man who developed HPS and SLE simultaneously. Febrile pancytopenia, hyperferritinemia, and abnormal liver function tests were observed. Hemophagocytic cells were observed by means of bone marrow biopsy and diagnosed as HPS. The patient was treated with high-dose prednisolone, resulting in an excellent outcome. Early diagnosis of HPS by bone marrow biopsy is important for the successful treatment.
AB - Hemophagocytic syndrome (HPS) is an unusual but sometimes fatal disorder. We reported a case of 21-year-old man who developed HPS and SLE simultaneously. Febrile pancytopenia, hyperferritinemia, and abnormal liver function tests were observed. Hemophagocytic cells were observed by means of bone marrow biopsy and diagnosed as HPS. The patient was treated with high-dose prednisolone, resulting in an excellent outcome. Early diagnosis of HPS by bone marrow biopsy is important for the successful treatment.
KW - Hemophagocytic syndrome
KW - Initial manifestation
KW - Systemic lupus erythematosus
UR - http://www.scopus.com/inward/record.url?scp=73649147042&partnerID=8YFLogxK
U2 - 10.1007/s00296-009-0932-5
DO - 10.1007/s00296-009-0932-5
M3 - 学術論文
C2 - 19381636
AN - SCOPUS:73649147042
SN - 0172-8172
VL - 30
SP - 387
EP - 388
JO - Rheumatology International
JF - Rheumatology International
IS - 3
ER -