Paradoxical prognostic impact of severe aortic stenosis following trans-catheter aortic valve implantation

研究成果: ジャーナルへの寄稿学術論文査読

2 被引用数 (Scopus)

抄録

Background: Aortic valve replacement is recommended for patients with “very severe” aortic stenosis (AS), irrespective of symptomatic manifestation. Nonetheless, the prognostic ramifications of “very severe” AS, as opposed to “severe” AS, subsequent to trans-catheter aortic valve implantation (TAVI) remain enigmatic. Methods: We enrolled consecutive patients who received TAVI at our institute between May 2015 and April 2021. We scrutinized the impact of baseline “very severe” AS upon 3-year all-cause death or heart failure hospitalization following TAVI, in comparison to “severe” AS. Results: A total of 239 patients (84.8 ± 5.4 years old, 58 men) were included. Baseline “very severe” AS was observed in 65 (27 %) patients, who exhibited more advanced hypertrophy and higher B-type natriuretic peptide levels compared to those with “severe” AS (p < 0.05 for both). Baseline “very severe” AS was paradoxically associated with higher freedom from the primary endpoint following TAVI compared to those with “severe” AS (p = 0.01). Conclusions: The presence of baseline “very severe” AS was paradoxically associated with improved clinical outcomes subsequent to TAVI, in contrast to the cases of “severe” AS.

本文言語英語
ページ(範囲)311-316
ページ数6
ジャーナルJournal of Cardiology
84
5
DOI
出版ステータス出版済み - 2024/11

ASJC Scopus 主題領域

  • 循環器および心血管医学

フィンガープリント

「Paradoxical prognostic impact of severe aortic stenosis following trans-catheter aortic valve implantation」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル