ONO-1301 loaded nanocomposite scaffolds modulate cAMP mediated signaling and induce new bone formation in critical sized bone defect

Keyphrases

• Cyclic Adenosine Monophosphate (cAMP) 100%
• New Bone Formation 100%
• ONO-1301 100%
• Critical-sized Bone Defect 100%
• Nanocomposite Scaffold 100%
• Small Molecules 50%
• Growth Factors 25%
• Mesenchymal Stem Cells 25%
• Sustained Release 25%
• Adverse Effects 25%
• Bone Regeneration 25%
• Regeneration 25%
• Angiogenesis 25%
• Prostaglandin Analogs 25%
• Prostaglandins 25%
• Reinforced 25%
• Osteogenic Differentiation 25%
• High Cost 25%
• Large-sized 25%
• Calvarial Defect 25%
• Osteoinductive 25%
• Angiogenic Potential 25%
• Bone Tissue Regeneration 25%
• Burst Release 25%
• Cost of Growth 25%
• Biomimetic Nanocomposite 25%
• Cyclic AMP Signaling Pathway 25%
• Osteoinduction 25%
• Osteoinductive Potential 25%
• Gel Matrix 25%
• Nano-hydroxyapatite (n-HA) 25%

Biochemistry, Genetics and Molecular Biology

• Cyclic Adenosine Monophosphate 100%
• Ossification 100%
• Small Molecule 100%
• Growth Factor 50%
• Stem Cell 50%
• Angiogenesis 50%
• Signal Transduction 50%
• Tissue Regeneration 50%
• Bone Regeneration 50%
• Sustained Drug Release 50%
• Prostacyclin 50%
• Prostacyclin Receptor 50%
• Biomimetics 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Bone Defect 100%
• Cyclic AMP 100%
• Nanocomposite 100%
• Sustained Release 50%
• Adverse Event 50%
• Growth Factor 50%
• Gelatin 50%
• Prostacyclin Derivative 50%
• Prostacyclin Receptor 50%