TY - JOUR
T1 - Numerical simulation validation of nonuniform, nonharmonic analysis of spectral-domain optical coherence tomography
AU - Uchida, Tetsuya
AU - Inuzuka, Yuya
AU - Hasegawa, Masaya
AU - Hirobayashi, Shigeki
AU - Misawa, Tadanobu
N1 - Publisher Copyright:
© 2015 Society of Photo-Optical Instrumentation Engineers (SPIE).
PY - 2015/3/1
Y1 - 2015/3/1
N2 - In spectral-domain optical coherence tomography (SD-OCT), the limited resolution of the spectrometer causes nonuniformity of the interference signal. The latter, in turn, causes the sensitivity of SD-OCT to decrease, thereby limiting the imaging range and decreasing the axial resolution. We addressed this problem by applying nonuniform, nonharmonic analysis (NUNHA) with software that features high-frequency resolution without interpolation. We demonstrate the application of NUNHA in SD-OCT and compare it with conventional frequency analysis methods by simulating nonuniform interference signals. The results suggest that application of NUNHA in SD-OCT can provide acquisition of a clearer tomographic image, accurate analysis of fine and complex structures, and preservation of resolution and sensitivity at regions deep within a sample. This is because it reduces the influence of nonuniformity caused by the spectrometer and is unaffected by distortion due to interpolation.
AB - In spectral-domain optical coherence tomography (SD-OCT), the limited resolution of the spectrometer causes nonuniformity of the interference signal. The latter, in turn, causes the sensitivity of SD-OCT to decrease, thereby limiting the imaging range and decreasing the axial resolution. We addressed this problem by applying nonuniform, nonharmonic analysis (NUNHA) with software that features high-frequency resolution without interpolation. We demonstrate the application of NUNHA in SD-OCT and compare it with conventional frequency analysis methods by simulating nonuniform interference signals. The results suggest that application of NUNHA in SD-OCT can provide acquisition of a clearer tomographic image, accurate analysis of fine and complex structures, and preservation of resolution and sensitivity at regions deep within a sample. This is because it reduces the influence of nonuniformity caused by the spectrometer and is unaffected by distortion due to interpolation.
KW - image reconstruction techniques
KW - optical coherence tomography
UR - http://www.scopus.com/inward/record.url?scp=84926034240&partnerID=8YFLogxK
U2 - 10.1117/1.OE.54.3.033108
DO - 10.1117/1.OE.54.3.033108
M3 - 学術論文
AN - SCOPUS:84926034240
SN - 0091-3286
VL - 54
JO - Optical Engineering
JF - Optical Engineering
IS - 3
M1 - 033108
ER -