@article{4a537767347740b3a417c05ae7ed5237,
title = "Neuroprotective effects of ethyl-eicosapentaenoic acid in first episode psychosis: A longitudinal T2 relaxometry pilot study",
abstract = "We used magnetic resonance imaging to examine the effect of ethyl-eicosapentaenoic acid (E-EPA) on hippocampal T2 relaxation time in first episode psychosis patients at baseline and after 12weeks of follow-up. There was an increase in T2 in the placebo group but not in the E-EPA group, suggesting a neuroprotective effect of E-EPA treatment. In addition, the smaller the increase in T2, the greater the improvement in negative symptoms.",
keywords = "Hippocampus, MRI, Neuroprotection, Schizophrenia",
author = "Wood, {Stephen J.} and Luca Cocchi and Proffitt, {Tina Marie} and Mirabel McConchie and Jackson, {Graeme D.} and Tsutomu Takahashi and Christos Pantelis and McGorry, {Patrick D.} and Berger, {Gregor E.}",
note = "Funding Information: This work was supported by two NH&MRC project grants (ID: 145627 ; 209062 ), a NH&MRC program grant (ID: 350241 ), and the Colonial Foundation, Melbourne, Australia . A/Prof Wood is supported by a Clinical Career Development Award from the NH&MRC, and Dr Cocchi by a Swiss National Science Foundation young investigator award ( PBLAB3-119622 ). A Margaret & Walter Lichtenstein Foundation award (University of Basel) supported Dr Berger. These funding sources had no further role in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the paper for publication. None of the authors has a conflict of interest with any manufacturer or distributor of omega-3 fatty acids. The presented data were part of an investigator-initiated trial. Laxdale Ltd (now owned by Amarin Corporation) provided the study medication for free. None of the research centres received any financial support from Laxdale Ltd.",
year = "2010",
month = may,
doi = "10.1016/j.pscychresns.2009.12.003",
language = "英語",
volume = "182",
pages = "180--182",
journal = "Psychiatry Research - Neuroimaging",
issn = "0925-4927",
publisher = "Elsevier Ireland Ltd",
number = "2",
}