Neurocognitive assessment and pharmacotherapy towards prevention of schizophrenia: What can we learn from first episode psychosis?

Research into first episode psychosis (FEP) is a growing field in psychiatry. In this paper, the authors provide an overview of neurocognitive findings and therapeutic approaches indicated for patients with FEP. Focus will be placed on evidence from neuropsychological assessment and brain imaging of electrophysiological activities, as well as the ability of some psychotropic drugs, such as second generation antipsychotics, to improve functional outcome. Efforts to identify biological signals characteristic of FEP are expected to facilitate early intervention into schizophrenia and related disorders.