Liver Cirrhosis

Terumi Takahara; Masaki Iwai; Wilson M.S. Tsui

doi:10.1007/978-981-13-6806-6_6

Liver Cirrhosis

Terumi Takahara^*, Masaki Iwai, Wilson M.S. Tsui

^*この論文の責任著者

消化器がん診断・治療学推進講座

研究成果: 書籍の章/レポート/会議録 › 章 › 査読

抄録

Liver cirrhosis is anatomically defined as a diffuse disruption of the normal architecture of the liver with fibrosis and nodule formation. It is the end result of fibrogenesis caused by chronic liver injury. The anatomical architecture is the same with any etiology: continuous inflammation or hepatocyte damage causes fibrogenesis, and fibers extend from central or portal area, and finally fibrous septa is completely formed to surround regenerative nodules. Thus liver cirrhosis is characterized with hepatocyte dysfunction and portal hypertension.

本文言語	英語
ホスト出版物のタイトル	Diagnosis of Liver Disease, Second Edition
出版社	Springer Singapore
ページ	61-73
ページ数	13
ISBN（電子版）	9789811368066
ISBN（印刷版）	9789811368059
DOI	https://doi.org/10.1007/978-981-13-6806-6_6
出版ステータス	出版済み - 2019/01/01

ASJC Scopus 主題領域

医学一般

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10.1007/978-981-13-6806-6_6

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title = "Liver Cirrhosis",

abstract = "Liver cirrhosis is anatomically defined as a diffuse disruption of the normal architecture of the liver with fibrosis and nodule formation. It is the end result of fibrogenesis caused by chronic liver injury. The anatomical architecture is the same with any etiology: continuous inflammation or hepatocyte damage causes fibrogenesis, and fibers extend from central or portal area, and finally fibrous septa is completely formed to surround regenerative nodules. Thus liver cirrhosis is characterized with hepatocyte dysfunction and portal hypertension.",

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AU - Iwai, Masaki

AU - Tsui, Wilson M.S.

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Y1 - 2019/1/1

N2 - Liver cirrhosis is anatomically defined as a diffuse disruption of the normal architecture of the liver with fibrosis and nodule formation. It is the end result of fibrogenesis caused by chronic liver injury. The anatomical architecture is the same with any etiology: continuous inflammation or hepatocyte damage causes fibrogenesis, and fibers extend from central or portal area, and finally fibrous septa is completely formed to surround regenerative nodules. Thus liver cirrhosis is characterized with hepatocyte dysfunction and portal hypertension.

AB - Liver cirrhosis is anatomically defined as a diffuse disruption of the normal architecture of the liver with fibrosis and nodule formation. It is the end result of fibrogenesis caused by chronic liver injury. The anatomical architecture is the same with any etiology: continuous inflammation or hepatocyte damage causes fibrogenesis, and fibers extend from central or portal area, and finally fibrous septa is completely formed to surround regenerative nodules. Thus liver cirrhosis is characterized with hepatocyte dysfunction and portal hypertension.

KW - Child-Pugh classification

KW - Elastography

KW - Fibrogenesis

KW - Hepatic stellate cell

KW - Hepatorenal syndrome

KW - MELD score

KW - Macronodule

KW - Micronodule

KW - Reversibility

KW - Spontaneous bacterial peritonitis

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BT - Diagnosis of Liver Disease, Second Edition

PB - Springer Singapore

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Liver Cirrhosis

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