Iodocyclization of ethoxyethyl ethers to alkynes: A broadly applicable synthesis of 3-iodobenzo[b]furans

Takashi Okitsu; Daisuke Nakazawa; Rie Taniguchi; Akimori Wada

doi:10.1021/ol8020463

Iodocyclization of ethoxyethyl ethers to alkynes: A broadly applicable synthesis of 3-iodobenzo[b]furans

Takashi Okitsu^*, Daisuke Nakazawa, Rie Taniguchi, Akimori Wada

^*この論文の責任著者

分子合成化学研究室

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

82 被引用数 (Scopus)

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(Chemical Equation Presented) A wide variety of 3-iodobenzo[b]furans were readily prepared by iodocyclization of 2-alkynyl-1-(1-ethoxyethoxy)benzenes with the I(coll)₂PF₆-BF₃-OEt₂ combination. Aryl-, vinyiic-, and alkyl-substituted alkynes undergo iodocyclization in good to excellent yields. The mechanism of the reaction is also discussed.

本文言語	英語
ページ（範囲）	4967-4970
ページ数	4
ジャーナル	Organic Letters
巻	10
号	21
DOI	https://doi.org/10.1021/ol8020463
出版ステータス	出版済み - 2008

ASJC Scopus 主題領域

生化学
物理化学および理論化学
有機化学

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10.1021/ol8020463

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title = "Iodocyclization of ethoxyethyl ethers to alkynes: A broadly applicable synthesis of 3-iodobenzo[b]furans",

abstract = "(Chemical Equation Presented) A wide variety of 3-iodobenzo[b]furans were readily prepared by iodocyclization of 2-alkynyl-1-(1-ethoxyethoxy)benzenes with the I(coll)2PF6-BF3-OEt2 combination. Aryl-, vinyiic-, and alkyl-substituted alkynes undergo iodocyclization in good to excellent yields. The mechanism of the reaction is also discussed.",

author = "Takashi Okitsu and Daisuke Nakazawa and Rie Taniguchi and Akimori Wada",

year = "2008",

doi = "10.1021/ol8020463",

language = "英語",

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journal = "Organic Letters",

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T1 - Iodocyclization of ethoxyethyl ethers to alkynes

T2 - A broadly applicable synthesis of 3-iodobenzo[b]furans

AU - Okitsu, Takashi

AU - Nakazawa, Daisuke

AU - Taniguchi, Rie

AU - Wada, Akimori

PY - 2008

Y1 - 2008

N2 - (Chemical Equation Presented) A wide variety of 3-iodobenzo[b]furans were readily prepared by iodocyclization of 2-alkynyl-1-(1-ethoxyethoxy)benzenes with the I(coll)2PF6-BF3-OEt2 combination. Aryl-, vinyiic-, and alkyl-substituted alkynes undergo iodocyclization in good to excellent yields. The mechanism of the reaction is also discussed.

AB - (Chemical Equation Presented) A wide variety of 3-iodobenzo[b]furans were readily prepared by iodocyclization of 2-alkynyl-1-(1-ethoxyethoxy)benzenes with the I(coll)2PF6-BF3-OEt2 combination. Aryl-, vinyiic-, and alkyl-substituted alkynes undergo iodocyclization in good to excellent yields. The mechanism of the reaction is also discussed.

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U2 - 10.1021/ol8020463

DO - 10.1021/ol8020463

M3 - 学術論文

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Iodocyclization of ethoxyethyl ethers to alkynes: A broadly applicable synthesis of 3-iodobenzo[b]furans

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