Intra-Mesenteric Artery Steroid Administration Relieved Severe Refractory Gastro-Intestinal Graft-Vs.-Host Disease in an Allogeneic Bone Marrow Transplantation Patient

Tsutomu Sato; Sumio Sakamaki; Yasuhiro Nagaoka; Kageaki Kuribayashi; Yasuhiro Nagamachi; Kazuhiro Morii; Hisato Honma; Katsuhisa Kogawa; Junji Kato; Yoshiro Niitsu

doi:10.1002/(SICI)1096-8652(199712)56:4<277::AID-AJH14>3.0.CO;2-6

Intra-Mesenteric Artery Steroid Administration Relieved Severe Refractory Gastro-Intestinal Graft-Vs.-Host Disease in an Allogeneic Bone Marrow Transplantation Patient

Tsutomu Sato^*, Sumio Sakamaki, Yasuhiro Nagaoka, Kageaki Kuribayashi, Yasuhiro Nagamachi, Kazuhiro Morii, Hisato Honma, Katsuhisa Kogawa, Junji Kato, Yoshiro Niitsu

^*この論文の責任著者

血液内科

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

15 被引用数 (Scopus)

抄録

We report a case of severe gastro-intestinal (G-I) gratt-vs.-host disease (GVHD) successfully treated with intra-mesenteric artery steroid administration. A 29-year-old man with severe aplastic anemia (SAA) was submitted to HLA-identical unrelated allogeneic bone marrow transplantation (BMT) and was found to be suffering from grade IV G-I GVHD. Although cyclosporine, steroid pulse therapy, and FK506 proved ineffective, 30 mg of water-soluble prednisolone as administered into each the superior and inferior mesenteric artery with remarkable effects. This treatment was repeated two times, and the symptoms of G-I GVHD disappeared completely.

本文言語	英語
ページ（範囲）	277-280
ページ数	4
ジャーナル	American Journal of Hematology
巻	56
号	4
DOI	https://doi.org/10.1002/(SICI)1096-8652(199712)56:4<277::AID-AJH14>3.0.CO;2-6
出版ステータス	出版済み - 1997/12

ASJC Scopus 主題領域

血液学

文献へのアクセス

10.1002/(SICI)1096-8652(199712)56:4<277::AID-AJH14>3.0.CO;2-6

フィンガープリント

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引用スタイル

Sato, T., Sakamaki, S., Nagaoka, Y., Kuribayashi, K., Nagamachi, Y., Morii, K., Honma, H., Kogawa, K., Kato, J., & Niitsu, Y. (1997). Intra-Mesenteric Artery Steroid Administration Relieved Severe Refractory Gastro-Intestinal Graft-Vs.-Host Disease in an Allogeneic Bone Marrow Transplantation Patient. American Journal of Hematology, 56(4), 277-280. https://doi.org/10.1002/(SICI)1096-8652(199712)56:4<277::AID-AJH14>3.0.CO;2-6

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title = "Intra-Mesenteric Artery Steroid Administration Relieved Severe Refractory Gastro-Intestinal Graft-Vs.-Host Disease in an Allogeneic Bone Marrow Transplantation Patient",

abstract = "We report a case of severe gastro-intestinal (G-I) gratt-vs.-host disease (GVHD) successfully treated with intra-mesenteric artery steroid administration. A 29-year-old man with severe aplastic anemia (SAA) was submitted to HLA-identical unrelated allogeneic bone marrow transplantation (BMT) and was found to be suffering from grade IV G-I GVHD. Although cyclosporine, steroid pulse therapy, and FK506 proved ineffective, 30 mg of water-soluble prednisolone as administered into each the superior and inferior mesenteric artery with remarkable effects. This treatment was repeated two times, and the symptoms of G-I GVHD disappeared completely.",

keywords = "Graft vs. host disease, Intraarterial injection, Steroid, Therapy, Ulcerative colitis",

author = "Tsutomu Sato and Sumio Sakamaki and Yasuhiro Nagaoka and Kageaki Kuribayashi and Yasuhiro Nagamachi and Kazuhiro Morii and Hisato Honma and Katsuhisa Kogawa and Junji Kato and Yoshiro Niitsu",

year = "1997",

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doi = "10.1002/(SICI)1096-8652(199712)56:4<277::AID-AJH14>3.0.CO;2-6",

language = "英語",

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Sato, T, Sakamaki, S, Nagaoka, Y, Kuribayashi, K, Nagamachi, Y, Morii, K, Honma, H, Kogawa, K, Kato, J & Niitsu, Y 1997, 'Intra-Mesenteric Artery Steroid Administration Relieved Severe Refractory Gastro-Intestinal Graft-Vs.-Host Disease in an Allogeneic Bone Marrow Transplantation Patient', American Journal of Hematology, vol. 56, no. 4, pp. 277-280. https://doi.org/10.1002/(SICI)1096-8652(199712)56:4<277::AID-AJH14>3.0.CO;2-6

Intra-Mesenteric Artery Steroid Administration Relieved Severe Refractory Gastro-Intestinal Graft-Vs.-Host Disease in an Allogeneic Bone Marrow Transplantation Patient. / Sato, Tsutomu; Sakamaki, Sumio; Nagaoka, Yasuhiro その他.
In: American Journal of Hematology, Vol. 56, No. 4, 12.1997, p. 277-280.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

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T1 - Intra-Mesenteric Artery Steroid Administration Relieved Severe Refractory Gastro-Intestinal Graft-Vs.-Host Disease in an Allogeneic Bone Marrow Transplantation Patient

AU - Sato, Tsutomu

AU - Sakamaki, Sumio

AU - Nagaoka, Yasuhiro

AU - Kuribayashi, Kageaki

AU - Nagamachi, Yasuhiro

AU - Morii, Kazuhiro

AU - Honma, Hisato

AU - Kogawa, Katsuhisa

AU - Kato, Junji

AU - Niitsu, Yoshiro

PY - 1997/12

Y1 - 1997/12

N2 - We report a case of severe gastro-intestinal (G-I) gratt-vs.-host disease (GVHD) successfully treated with intra-mesenteric artery steroid administration. A 29-year-old man with severe aplastic anemia (SAA) was submitted to HLA-identical unrelated allogeneic bone marrow transplantation (BMT) and was found to be suffering from grade IV G-I GVHD. Although cyclosporine, steroid pulse therapy, and FK506 proved ineffective, 30 mg of water-soluble prednisolone as administered into each the superior and inferior mesenteric artery with remarkable effects. This treatment was repeated two times, and the symptoms of G-I GVHD disappeared completely.

AB - We report a case of severe gastro-intestinal (G-I) gratt-vs.-host disease (GVHD) successfully treated with intra-mesenteric artery steroid administration. A 29-year-old man with severe aplastic anemia (SAA) was submitted to HLA-identical unrelated allogeneic bone marrow transplantation (BMT) and was found to be suffering from grade IV G-I GVHD. Although cyclosporine, steroid pulse therapy, and FK506 proved ineffective, 30 mg of water-soluble prednisolone as administered into each the superior and inferior mesenteric artery with remarkable effects. This treatment was repeated two times, and the symptoms of G-I GVHD disappeared completely.

KW - Graft vs. host disease

KW - Intraarterial injection

KW - Steroid

KW - Therapy

KW - Ulcerative colitis

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SN - 0361-8609

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JO - American Journal of Hematology

JF - American Journal of Hematology

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Sato T, Sakamaki S, Nagaoka Y, Kuribayashi K, Nagamachi Y, Morii K その他. Intra-Mesenteric Artery Steroid Administration Relieved Severe Refractory Gastro-Intestinal Graft-Vs.-Host Disease in an Allogeneic Bone Marrow Transplantation Patient. American Journal of Hematology. 1997 12月;56(4):277-280. doi: 10.1002/(SICI)1096-8652(199712)56:4<277::AID-AJH14>3.0.CO;2-6