Impact of genetic background and ablation of insulin receptor substrate (IRS)-3 on IRS-2 knock-out mice

Keyphrases

• Knock-in Mouse Model 100%
• IRS2 100%
• Genetic Background 100%
• Insulin Receptor Substrate 1 (IRS1) 100%
• Genetic Ablation 100%
• Diabetes 36%
• Glucose Homeostasis 10%
• Insulin Resistance 10%
• Cell Mass 10%
• A1 Receptor 10%
• Genotype 10%
• Double Knockout 10%
• Glucose Intolerance 5%
• Pdx1 5%
• Glucose Tolerance Test 5%
• Islet 5%
• Insulin 5%
• Ablation 5%
• Without Diabetes 5%
• Hyperglycemia 5%
• Blood Glucose 5%
• Insulin Tolerance Test 5%
• Glucose-insulin System 5%
• Null mutation 5%
• Glucose Transporter 2 (GLUT2) 5%
• Two-line 5%
• 2 Receptor 5%
• Reduced Cell 5%
• Normal Blood 5%
• Normal Growth 5%
• Apparently Healthy 5%
• Intercross 5%
• Genetic Strain 5%
• Modifier Genes 5%

Biochemistry, Genetics and Molecular Biology

• Genetic Background 100%
• Knockout Mouse 100%
• Genetic Ablation 100%
• Insulin Receptor 100%
• Glucose Homeostasis 5%
• Insulin Resistance 5%
• Genotyping 2%
• Insulin Tolerance Test 2%
• Glucose Blood Level 2%
• Hyperglycemia 2%
• Genetic Strain 2%
• Modifier Gene 2%
• 129 Mouse 2%
• CBA Mouse 2%
• Glucose Transporter 2%