@article{c8ed213ace574443a8d62a76871b3367,
title = "Identification and characterization of a novel zebrafish semaphorin",
abstract = "The semaphorin gene family contains numerous secreted and transmembrane proteins. Some of them function as the repulsive and attractive axon guidance molecules during development. Herein, we report the cloning and characterization of a novel member of zebrafish semaphorin gene, semaphorin 6. E (sema6. E). Sema6. E is expressed predominantly in the nervous system during embryogenesis. Results also show that Sema6E binds Plexin-A1, but not other Plexins. Sema6E chemorepels not only dorsal root ganglion axons but also sympathetic axons. Therefore, Sema6E might utilize Plexin-A1 as a receptor to repel axons of the specific types during development.",
keywords = "Axon guidance, Brain, Lens, Plexin, Repellent, Semaphorin",
author = "Masahiko Taniguchi and Tomoyuki Masuda and Yoshinori Mikami and Masafumi Kimura and Tomoyuki Yoshida and Masayoshi Mishina and Takao Shimizu",
note = "Funding Information: We are grateful to Dr. Hitoshi Okamoto (RIKEN, BSI) for the gift of zebrafish Plexin-A4 expression vector. This work was supported by Grants-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science (JSPS) , The Suhara Memorial Foundation , and The Akiyama Life Science Foundation .",
year = "2011",
month = jan,
day = "20",
doi = "10.1016/j.neulet.2010.11.032",
language = "英語",
volume = "488",
pages = "215--220",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "2",
}