Global estimates on the number of people blind or visually impaired by age-related macular degeneration: a meta-analysis from 2000 to 2020

Vision Loss Expert Group of the Global Burden of Disease Study; the GBD 2019 Blindness and Vision Impairment Collaborators

doi:10.1038/s41433-024-03050-z

Global estimates on the number of people blind or visually impaired by age-related macular degeneration: a meta-analysis from 2000 to 2020

Vision Loss Expert Group of the Global Burden of Disease Study, the GBD 2019 Blindness and Vision Impairment Collaborators

医療統計学講座

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

11 被引用数 (Scopus)

抄録

Background: We aimed to update estimates of global vision loss due to age-related macular degeneration (AMD). Methods: We did a systematic review and meta-analysis of population-based surveys of eye diseases from January, 1980, to October, 2018. We fitted hierarchical models to estimate the prevalence of moderate and severe vision impairment (MSVI; presenting visual acuity from <6/18 to 3/60) and blindness (< 3/60) caused by AMD, stratified by age, region, and year. Results: In 2020, 1.85 million (95%UI: 1.35 to 2.43 million) people were estimated to be blind due to AMD, and another 6.23 million (95%UI: 5.04 to 7.58) with MSVI globally. High-income countries had the highest number of individuals with AMD-related blindness (0.60 million people; 0.46 to 0.77). The crude prevalence of AMD-related blindness in 2020 (among those aged ≥ 50 years) was 0.10% (0.07 to 0.12) globally, and the region with the highest prevalence of AMD-related blindness was North Africa/Middle East (0.22%; 0.16 to 0.30). Age-standardized prevalence (using the GBD 2019 data) of AMD-related MSVI in people aged ≥ 50 years in 2020 was 0.34% (0.27 to 0.41) globally, and the region with the highest prevalence of AMD-related MSVI was also North Africa/Middle East (0.55%; 0.44 to 0.68). From 2000 to 2020, the estimated crude prevalence of AMD-related blindness decreased globally by 19.29%, while the prevalence of MSVI increased by 10.08%. Conclusions: The estimated increase in the number of individuals with AMD-related blindness and MSVI globally urges the creation of novel treatment modalities and the expansion of rehabilitation services.

本文言語	英語
ページ（範囲）	2070-2082
ページ数	13
ジャーナル	Eye (Basingstoke)
巻	38
号	11
DOI	https://doi.org/10.1038/s41433-024-03050-z
出版ステータス	出版済み - 2024/08

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眼科学
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10.1038/s41433-024-03050-z

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引用スタイル

@article{6ddb0b891bb44ab5b7ce7d64f8b90816,

title = "Global estimates on the number of people blind or visually impaired by age-related macular degeneration: a meta-analysis from 2000 to 2020",

abstract = "Background: We aimed to update estimates of global vision loss due to age-related macular degeneration (AMD). Methods: We did a systematic review and meta-analysis of population-based surveys of eye diseases from January, 1980, to October, 2018. We fitted hierarchical models to estimate the prevalence of moderate and severe vision impairment (MSVI; presenting visual acuity from <6/18 to 3/60) and blindness (< 3/60) caused by AMD, stratified by age, region, and year. Results: In 2020, 1.85 million (95%UI: 1.35 to 2.43 million) people were estimated to be blind due to AMD, and another 6.23 million (95%UI: 5.04 to 7.58) with MSVI globally. High-income countries had the highest number of individuals with AMD-related blindness (0.60 million people; 0.46 to 0.77). The crude prevalence of AMD-related blindness in 2020 (among those aged ≥ 50 years) was 0.10% (0.07 to 0.12) globally, and the region with the highest prevalence of AMD-related blindness was North Africa/Middle East (0.22%; 0.16 to 0.30). Age-standardized prevalence (using the GBD 2019 data) of AMD-related MSVI in people aged ≥ 50 years in 2020 was 0.34% (0.27 to 0.41) globally, and the region with the highest prevalence of AMD-related MSVI was also North Africa/Middle East (0.55%; 0.44 to 0.68). From 2000 to 2020, the estimated crude prevalence of AMD-related blindness decreased globally by 19.29%, while the prevalence of MSVI increased by 10.08%. Conclusions: The estimated increase in the number of individuals with AMD-related blindness and MSVI globally urges the creation of novel treatment modalities and the expansion of rehabilitation services.",

author = "{Vision Loss Expert Group of the Global Burden of Disease Study} and {the GBD 2019 Blindness and Vision Impairment Collaborators} and Furtado, {Jo{\~a}o M.} and Jonas, {Jost B.} and Ian Tapply and Fernandes, {Arthur G.} and Cicinelli, {Maria Vittoria} and Alessandro Arrigo and Nicolas Leveziel and Serge Resnikoff and Taylor, {Hugh R.} and Tabassom Sedighi and Seth Flaxman and {Battaglia Parodi}, Maurizio and Bikbov, {Mukkharram M.} and Tasanee Braithwaite and Alain Bron and Cheng, {Ching Yu} and Nathan Congdon and {Del Monte}, {Monte A.} and Ehrlich, {Joshua R.} and Tim Fricke and David Friedman and Gus Gazzard and Hartnett, {M. Elizabeth} and Rim Kahloun and Kempen, {John H.} and Moncef Khairallah and Khanna, {Rohit C.} and Kim, {Judy E.} and Lansingh, {Van Charles} and Janet Leasher and Naidoo, {Kovin S.} and Vinay Nangia and Michal Nowak and Konrad Pesudovs and Tunde Peto and Pradeep Ramulu and Fotis Topouzis and Mitiadis Tsilimbaris and Wang, {Ya Xing} and Ningli Wang and Bourne, {Rupert R.A.} and Furtado, {Jo{\~a}o M.} and Fernandes, {Arthur G.} and Cicinelli, {Maria Vittoria} and Nicolas Leveziel and Briant, {Paul Svitil} and Theo Vos and Florian Fischer and Abate, {Yohannes Habtegiorgis} and Naohiro Yonemoto",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2024.",

year = "2024",

month = aug,

doi = "10.1038/s41433-024-03050-z",

language = "英語",

volume = "38",

pages = "2070--2082",

journal = "Eye (Basingstoke)",

issn = "0950-222X",

publisher = "Springer Nature",

number = "11",

}

Global estimates on the number of people blind or visually impaired by age-related macular degeneration: a meta-analysis from 2000 to 2020. / Vision Loss Expert Group of the Global Burden of Disease Study; the GBD 2019 Blindness and Vision Impairment Collaborators.
In: Eye (Basingstoke), Vol. 38, No. 11, 08.2024, p. 2070-2082.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

TY - JOUR

T1 - Global estimates on the number of people blind or visually impaired by age-related macular degeneration

T2 - a meta-analysis from 2000 to 2020

AU - Vision Loss Expert Group of the Global Burden of Disease Study

AU - the GBD 2019 Blindness and Vision Impairment Collaborators

AU - Furtado, João M.

AU - Jonas, Jost B.

AU - Tapply, Ian

AU - Fernandes, Arthur G.

AU - Cicinelli, Maria Vittoria

AU - Arrigo, Alessandro

AU - Leveziel, Nicolas

AU - Resnikoff, Serge

AU - Taylor, Hugh R.

AU - Sedighi, Tabassom

AU - Flaxman, Seth

AU - Battaglia Parodi, Maurizio

AU - Bikbov, Mukkharram M.

AU - Braithwaite, Tasanee

AU - Bron, Alain

AU - Cheng, Ching Yu

AU - Congdon, Nathan

AU - Del Monte, Monte A.

AU - Ehrlich, Joshua R.

AU - Fricke, Tim

AU - Friedman, David

AU - Gazzard, Gus

AU - Hartnett, M. Elizabeth

AU - Kahloun, Rim

AU - Kempen, John H.

AU - Khairallah, Moncef

AU - Khanna, Rohit C.

AU - Kim, Judy E.

AU - Lansingh, Van Charles

AU - Leasher, Janet

AU - Naidoo, Kovin S.

AU - Nangia, Vinay

AU - Nowak, Michal

AU - Pesudovs, Konrad

AU - Peto, Tunde

AU - Ramulu, Pradeep

AU - Topouzis, Fotis

AU - Tsilimbaris, Mitiadis

AU - Wang, Ya Xing

AU - Wang, Ningli

AU - Bourne, Rupert R.A.

AU - Furtado, João M.

AU - Fernandes, Arthur G.

AU - Cicinelli, Maria Vittoria

AU - Leveziel, Nicolas

AU - Briant, Paul Svitil

AU - Vos, Theo

AU - Fischer, Florian

AU - Abate, Yohannes Habtegiorgis

AU - Yonemoto, Naohiro

PY - 2024/8

Y1 - 2024/8

N2 - Background: We aimed to update estimates of global vision loss due to age-related macular degeneration (AMD). Methods: We did a systematic review and meta-analysis of population-based surveys of eye diseases from January, 1980, to October, 2018. We fitted hierarchical models to estimate the prevalence of moderate and severe vision impairment (MSVI; presenting visual acuity from <6/18 to 3/60) and blindness (< 3/60) caused by AMD, stratified by age, region, and year. Results: In 2020, 1.85 million (95%UI: 1.35 to 2.43 million) people were estimated to be blind due to AMD, and another 6.23 million (95%UI: 5.04 to 7.58) with MSVI globally. High-income countries had the highest number of individuals with AMD-related blindness (0.60 million people; 0.46 to 0.77). The crude prevalence of AMD-related blindness in 2020 (among those aged ≥ 50 years) was 0.10% (0.07 to 0.12) globally, and the region with the highest prevalence of AMD-related blindness was North Africa/Middle East (0.22%; 0.16 to 0.30). Age-standardized prevalence (using the GBD 2019 data) of AMD-related MSVI in people aged ≥ 50 years in 2020 was 0.34% (0.27 to 0.41) globally, and the region with the highest prevalence of AMD-related MSVI was also North Africa/Middle East (0.55%; 0.44 to 0.68). From 2000 to 2020, the estimated crude prevalence of AMD-related blindness decreased globally by 19.29%, while the prevalence of MSVI increased by 10.08%. Conclusions: The estimated increase in the number of individuals with AMD-related blindness and MSVI globally urges the creation of novel treatment modalities and the expansion of rehabilitation services.

AB - Background: We aimed to update estimates of global vision loss due to age-related macular degeneration (AMD). Methods: We did a systematic review and meta-analysis of population-based surveys of eye diseases from January, 1980, to October, 2018. We fitted hierarchical models to estimate the prevalence of moderate and severe vision impairment (MSVI; presenting visual acuity from <6/18 to 3/60) and blindness (< 3/60) caused by AMD, stratified by age, region, and year. Results: In 2020, 1.85 million (95%UI: 1.35 to 2.43 million) people were estimated to be blind due to AMD, and another 6.23 million (95%UI: 5.04 to 7.58) with MSVI globally. High-income countries had the highest number of individuals with AMD-related blindness (0.60 million people; 0.46 to 0.77). The crude prevalence of AMD-related blindness in 2020 (among those aged ≥ 50 years) was 0.10% (0.07 to 0.12) globally, and the region with the highest prevalence of AMD-related blindness was North Africa/Middle East (0.22%; 0.16 to 0.30). Age-standardized prevalence (using the GBD 2019 data) of AMD-related MSVI in people aged ≥ 50 years in 2020 was 0.34% (0.27 to 0.41) globally, and the region with the highest prevalence of AMD-related MSVI was also North Africa/Middle East (0.55%; 0.44 to 0.68). From 2000 to 2020, the estimated crude prevalence of AMD-related blindness decreased globally by 19.29%, while the prevalence of MSVI increased by 10.08%. Conclusions: The estimated increase in the number of individuals with AMD-related blindness and MSVI globally urges the creation of novel treatment modalities and the expansion of rehabilitation services.

UR - http://www.scopus.com/inward/record.url?scp=85199813397&partnerID=8YFLogxK

U2 - 10.1038/s41433-024-03050-z

DO - 10.1038/s41433-024-03050-z

M3 - 学術論文

C2 - 38965321

AN - SCOPUS:85199813397

SN - 0950-222X

VL - 38

SP - 2070

EP - 2082

JO - Eye (Basingstoke)

JF - Eye (Basingstoke)

IS - 11

ER -