Formation of Toxic Aβ(1-40) Fibrils on GM1 Ganglioside-Containing Membranes Mimicking Lipid Rafts: Polymorphisms in Aβ(1-40) Fibrils

Keyphrases

• Lipid Rafts 100%
• Amyloid Fibrils 100%
• GM1 Ganglioside 100%
• Polymorphism 100%
• Raft 100%
• Circular Dichroism 50%
• Transmission Electron Microscopy 50%
• Liposomes 50%
• Neuronal Cells 50%
• Cholesterol 50%
• Less Toxic 50%
• Alzheimer's Disease 50%
• Cell Membrane 50%
• Amyloid Protein 50%
• Sphingomyelin 50%
• Viability Assay 50%
• Lag Period 50%
• Circular Transmission 50%
• Abnormal Aggregation 50%
• Soluble Oligomers 50%
• Model Membranes 50%
• Thioflavin T 50%
• Neuronal PC12 Cells 50%
• Weak Binding 50%
• Secondary Structure 50%
• Small Surfaces 50%
• Gangliosides 50%
• Surface Hydrophobicity 50%

Biochemistry, Genetics and Molecular Biology

• Lipid Raft 100%
• GM1 100%
• Amyloid Protein 100%
• Ganglioside 100%
• Circular Dichroism 33%
• Cell Membrane 33%
• Protein Secondary Structure 33%
• Transmission Electron Microscopy 33%
• Thioflavin 33%
• Artificial Membrane 33%
• Hydrophobicity 33%
• Sphingomyelin 33%

Chemistry

• Ganglioside GM1 100%
• Toxic 100%
• formation 100%
• Amyloid Fibril 33%
• Oligomer 33%
• Circular Dichroism 16%
• Hydrophobicity 16%
• Transmission Electron Microscopy 16%
• Amyloid 16%
• Liposome 16%
• Secondary Structure 16%
• Ganglioside 16%
• Sphingomyelin 16%