TY - JOUR
T1 - First identification of potential bioactive compounds from ethanol extracts of Lepista sordida from Indonesia
AU - Nurhayat, O. D.
AU - Putra, I. P.
AU - Sibero, M. T.
AU - Hermawan, R.
AU - Karimah, S. N.
AU - Anita, S. H.
AU - Yanto, D. H.Y.
AU - Kristanto, M. A.
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2023
Y1 - 2023
N2 - Mushrooms species are well known to have a high potential for bioactive compounds for decades. In the era of modern technologies, it is possible to uncover and explore the hidden ethnopharmacological values, comprising complex bioactive compounds of substantial health benefits. Lepista sordida is an edible and medicinal mushroom, and its distributed from Europe to Southeast Asia. However, there was no prior study on the bioactive compounds of L. sordida from Indonesia. In this present study, ethanol extracts of L. sordida were obtained and their extract properties were determined by gas chromatography-mass spectrometry (GC-MS). A total of 13 different chemical compounds were found in L. sordida ethanol extracts through GC-MS analysis. 4-O-Methylmannose, n-Hexadecanoic acid, and cis-13-Octadecenoic acid were noted as the major compounds with area percentages of 10.09%, 8.19%, and 6.49%, respectively. The result of PASS Server analysis suggested that the ethanolic extract of L. sordida has the pharmaceutical effect to treat phobic disorder and skin damage, preventing blood clotting, anti-inflammatory, and treating several infections which cause by bacteria, protozoa, and viruses. Therefore, it is strongly suggested to conduct further bioassay to confirm the pharmaceutical properties of this mushroom.
AB - Mushrooms species are well known to have a high potential for bioactive compounds for decades. In the era of modern technologies, it is possible to uncover and explore the hidden ethnopharmacological values, comprising complex bioactive compounds of substantial health benefits. Lepista sordida is an edible and medicinal mushroom, and its distributed from Europe to Southeast Asia. However, there was no prior study on the bioactive compounds of L. sordida from Indonesia. In this present study, ethanol extracts of L. sordida were obtained and their extract properties were determined by gas chromatography-mass spectrometry (GC-MS). A total of 13 different chemical compounds were found in L. sordida ethanol extracts through GC-MS analysis. 4-O-Methylmannose, n-Hexadecanoic acid, and cis-13-Octadecenoic acid were noted as the major compounds with area percentages of 10.09%, 8.19%, and 6.49%, respectively. The result of PASS Server analysis suggested that the ethanolic extract of L. sordida has the pharmaceutical effect to treat phobic disorder and skin damage, preventing blood clotting, anti-inflammatory, and treating several infections which cause by bacteria, protozoa, and viruses. Therefore, it is strongly suggested to conduct further bioassay to confirm the pharmaceutical properties of this mushroom.
KW - Ethnopharmacological
KW - Lepista
KW - mushrooms
KW - PASS Server
KW - pharmaceutical
UR - http://www.scopus.com/inward/record.url?scp=85182012847&partnerID=8YFLogxK
U2 - 10.1088/1755-1315/1271/1/012058
DO - 10.1088/1755-1315/1271/1/012058
M3 - 会議記事
AN - SCOPUS:85182012847
SN - 1755-1307
VL - 1271
JO - IOP Conference Series: Earth and Environmental Science
JF - IOP Conference Series: Earth and Environmental Science
IS - 1
M1 - 012058
T2 - 5th International Conference on Biosciences, ICOBIO 2023
Y2 - 2 August 2023 through 3 August 2023
ER -