@article{a3d03a437a084317b3994263c38bfb23,
title = "Expression of a heparan sulfate remodeling enzyme, heparan sulfate 6-O-endosulfatase sulfatase FP2, in the rat nervous system",
abstract = "A new class of sulfatases, SulfFP1/sulf-1 and SulfFP2/sulf-2, has been implicated in the modulation of extracellular signaling by remodeling heparan sulfate through 6-O-endosulfatase activity. Here, we isolated rat SulfFP2 cDNA and examined its expression by in situ hybridization. SulfFP2 expression is abundant and dynamically regulated in the nervous system during development, whereas it is confined to the cerebral cortex, hippocampal CA3 region, and medial habenular nucleus in the adult brain.",
keywords = "Cerebral cortex, Floor plate, Heparan sulfate, Hippocampus, In situ hybridization, Sulfatase",
author = "Satoshi Nagamine and Seiichi Koike and Kazuko Keino-Masu and Masayuki Masu",
note = "Funding Information: This work was supported by Grants-in-Aid for Scientific Research on Priority Areas and the 21st century COE program from the Ministry of Education, Culture, Sports, Science, and Technology, Japan, and grants from the NOVARTIS Foundation (Japan) and Inamori Foundation. We thank K. Moriyoshi and S. Nakanishi for a rat brain cDNA library, and Y. Hatanaka and K. Shiomi for critical reading of the manuscript. ",
year = "2005",
month = oct,
day = "6",
doi = "10.1016/j.devbrainres.2005.07.006",
language = "英語",
volume = "159",
pages = "135--143",
journal = "Developmental Brain Research",
issn = "0165-3806",
publisher = "Elsevier B.V.",
number = "2",
}