Efficient synthesis of thioesters and amides from aldehydes by using an intermolecular radical reaction in water

Hisanori Nambu; Kayoko Hata; Masato Matsugi; Yasuyuki Kita

doi:10.1002/chem.200400754

Efficient synthesis of thioesters and amides from aldehydes by using an intermolecular radical reaction in water

Hisanori Nambu, Kayoko Hata, Masato Matsugi, Yasuyuki Kita^*

^*この論文の責任著者

分子合成化学研究室

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

63 被引用数 (Scopus)

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The combination of the water-soluble radical initiator, 2,2′-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride (VA-044) and the surfactant, cetyltrimethyl-ammonium bromide (CTAB), was found to be the most suitable condition for the effective and direct synthesis of useful active thioesters (pentafluorophenyl thioesters) in water. In addition, the direct amidation of aldehydes was achieved by the addition of the amines to the thioesterification reaction mixture in water.

本文言語	英語
ページ（範囲）	719-727
ページ数	9
ジャーナル	Chemistry - A European Journal
巻	11
号	2
DOI	https://doi.org/10.1002/chem.200400754
出版ステータス	出版済み - 2005/01/07

ASJC Scopus 主題領域

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10.1002/chem.200400754

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abstract = "The combination of the water-soluble radical initiator, 2,2′-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride (VA-044) and the surfactant, cetyltrimethyl-ammonium bromide (CTAB), was found to be the most suitable condition for the effective and direct synthesis of useful active thioesters (pentafluorophenyl thioesters) in water. In addition, the direct amidation of aldehydes was achieved by the addition of the amines to the thioesterification reaction mixture in water.",

keywords = "Aldehydes, Amidation, Radical reactions, Surfactants, Thioesters",

author = "Hisanori Nambu and Kayoko Hata and Masato Matsugi and Yasuyuki Kita",

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T1 - Efficient synthesis of thioesters and amides from aldehydes by using an intermolecular radical reaction in water

AU - Nambu, Hisanori

AU - Hata, Kayoko

AU - Matsugi, Masato

AU - Kita, Yasuyuki

PY - 2005/1/7

Y1 - 2005/1/7

N2 - The combination of the water-soluble radical initiator, 2,2′-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride (VA-044) and the surfactant, cetyltrimethyl-ammonium bromide (CTAB), was found to be the most suitable condition for the effective and direct synthesis of useful active thioesters (pentafluorophenyl thioesters) in water. In addition, the direct amidation of aldehydes was achieved by the addition of the amines to the thioesterification reaction mixture in water.

AB - The combination of the water-soluble radical initiator, 2,2′-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride (VA-044) and the surfactant, cetyltrimethyl-ammonium bromide (CTAB), was found to be the most suitable condition for the effective and direct synthesis of useful active thioesters (pentafluorophenyl thioesters) in water. In addition, the direct amidation of aldehydes was achieved by the addition of the amines to the thioesterification reaction mixture in water.

KW - Aldehydes

KW - Amidation

KW - Radical reactions

KW - Surfactants

KW - Thioesters

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M3 - 学術論文

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AN - SCOPUS:12444342979

SN - 0947-6539

VL - 11

SP - 719

EP - 727

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 2

ER -

Efficient synthesis of thioesters and amides from aldehydes by using an intermolecular radical reaction in water

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