抄録
An environmentally friendly oxidative cleavage of tetrahydrofuran-2-methanols to the corresponding γ-lactones using a catalytic amount of 2-iodo-N-isopropylbenzamide has been developed. The reaction of various tetrahydrofuran-2-methanols with the catalyst in the presence of Oxone® (2 KHSO5·KHSO4·K2SO4) as a co-oxidant in DMF at room temperature successfully affords the corresponding lactones in good to high yields, and recovery of the catalyst is readily accomplished using a reductive work-up. This method is notable because it enables the transformation of tetrahydrofuran-2-methanols to γ-lactones under mild conditions without the use of any toxic heavy metals.
本文言語 | 英語 |
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ページ(範囲) | 869-873 |
ページ数 | 5 |
ジャーナル | Advanced Synthesis and Catalysis |
巻 | 358 |
号 | 6 |
DOI | |
出版ステータス | 出版済み - 2016/03/17 |
ASJC Scopus 主題領域
- 触媒
- 有機化学