Direct Deuteration of Acrylic and Methacrylic Acid Derivatives Catalyzed by Platinum on Carbon in Deuterium Oxide

Kwihwan Park; Takumi Matsuda; Tsuyoshi Yamada; Yasunari Monguchi; Yuka Sawama; Naoki Doi; Yasushi Sasai; Shin Ichi Kondo; Yoshinari Sawama; Hironao Sajiki

doi:10.1002/adsc.201800170

Direct Deuteration of Acrylic and Methacrylic Acid Derivatives Catalyzed by Platinum on Carbon in Deuterium Oxide

Kwihwan Park, Takumi Matsuda, Tsuyoshi Yamada, Yasunari Monguchi, Yuka Sawama, Naoki Doi, Yasushi Sasai, Shin Ichi Kondo, Yoshinari Sawama^*, Hironao Sajiki

^*この論文の責任著者

薬品製造学研究室

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

34 被引用数 (Scopus)

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The platinum on carbon (Pt/C)-catalyzed deuteration of acrylic and methacrylic acid derivatives in deuterium oxide (D₂O) efficiently proceeded to give the corresponding acrylic acid-d₃ and methacrylic acid-d₅ derivatives. The olefinic functionality, as well as the methyl group on the unsaturated functionality of the substrate, were satisfactorily deuterated via the hydrogen (H)-deuterium (D) exchange reaction. The obtained deuterated compounds are useful building blocks and efficiently converted to the corresponding desired products including a polymer without the degradation of the original deuterium contents. (Figure presented.).

本文言語	英語
ページ（範囲）	2303-2307
ページ数	5
ジャーナル	Advanced Synthesis and Catalysis
巻	360
号	12
DOI	https://doi.org/10.1002/adsc.201800170
出版ステータス	出版済み - 2018/06/15

ASJC Scopus 主題領域

触媒
有機化学

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10.1002/adsc.201800170

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title = "Direct Deuteration of Acrylic and Methacrylic Acid Derivatives Catalyzed by Platinum on Carbon in Deuterium Oxide",

abstract = "The platinum on carbon (Pt/C)-catalyzed deuteration of acrylic and methacrylic acid derivatives in deuterium oxide (D2O) efficiently proceeded to give the corresponding acrylic acid-d3 and methacrylic acid-d5 derivatives. The olefinic functionality, as well as the methyl group on the unsaturated functionality of the substrate, were satisfactorily deuterated via the hydrogen (H)-deuterium (D) exchange reaction. The obtained deuterated compounds are useful building blocks and efficiently converted to the corresponding desired products including a polymer without the degradation of the original deuterium contents. (Figure presented.).",

keywords = "deuterated polymer, deuteration, deuterium oxide, hydrogenation free, platinum on carbon",

author = "Kwihwan Park and Takumi Matsuda and Tsuyoshi Yamada and Yasunari Monguchi and Yuka Sawama and Naoki Doi and Yasushi Sasai and Kondo, {Shin Ichi} and Yoshinari Sawama and Hironao Sajiki",

note = "Publisher Copyright: {\textcopyright} 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",

year = "2018",

month = jun,

day = "15",

doi = "10.1002/adsc.201800170",

language = "英語",

volume = "360",

pages = "2303--2307",

journal = "Advanced Synthesis and Catalysis",

issn = "1615-4150",

publisher = "Wiley-VCH Verlag",

number = "12",

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TY - JOUR

T1 - Direct Deuteration of Acrylic and Methacrylic Acid Derivatives Catalyzed by Platinum on Carbon in Deuterium Oxide

AU - Park, Kwihwan

AU - Matsuda, Takumi

AU - Yamada, Tsuyoshi

AU - Monguchi, Yasunari

AU - Sawama, Yuka

AU - Doi, Naoki

AU - Sasai, Yasushi

AU - Kondo, Shin Ichi

AU - Sawama, Yoshinari

AU - Sajiki, Hironao

PY - 2018/6/15

Y1 - 2018/6/15

N2 - The platinum on carbon (Pt/C)-catalyzed deuteration of acrylic and methacrylic acid derivatives in deuterium oxide (D2O) efficiently proceeded to give the corresponding acrylic acid-d3 and methacrylic acid-d5 derivatives. The olefinic functionality, as well as the methyl group on the unsaturated functionality of the substrate, were satisfactorily deuterated via the hydrogen (H)-deuterium (D) exchange reaction. The obtained deuterated compounds are useful building blocks and efficiently converted to the corresponding desired products including a polymer without the degradation of the original deuterium contents. (Figure presented.).

AB - The platinum on carbon (Pt/C)-catalyzed deuteration of acrylic and methacrylic acid derivatives in deuterium oxide (D2O) efficiently proceeded to give the corresponding acrylic acid-d3 and methacrylic acid-d5 derivatives. The olefinic functionality, as well as the methyl group on the unsaturated functionality of the substrate, were satisfactorily deuterated via the hydrogen (H)-deuterium (D) exchange reaction. The obtained deuterated compounds are useful building blocks and efficiently converted to the corresponding desired products including a polymer without the degradation of the original deuterium contents. (Figure presented.).

KW - deuterated polymer

KW - deuteration

KW - deuterium oxide

KW - hydrogenation free

KW - platinum on carbon

UR - http://www.scopus.com/inward/record.url?scp=85046277819&partnerID=8YFLogxK

U2 - 10.1002/adsc.201800170

DO - 10.1002/adsc.201800170

M3 - 学術論文

AN - SCOPUS:85046277819

SN - 1615-4150

VL - 360

SP - 2303

EP - 2307

JO - Advanced Synthesis and Catalysis

JF - Advanced Synthesis and Catalysis

IS - 12

ER -

Direct Deuteration of Acrylic and Methacrylic Acid Derivatives Catalyzed by Platinum on Carbon in Deuterium Oxide

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