TY - JOUR
T1 - Dietary intake of fish and n-3 polyunsaturated fatty acids and risk of postpartum depression
T2 - A nationwide longitudinal study - The Japan Environment and Children's Study (JECS)
AU - Hamazaki, Kei
AU - Matsumura, Kenta
AU - Tsuchida, Akiko
AU - Kasamatsu, Haruka
AU - Tanaka, Tomomi
AU - Ito, Mika
AU - Inadera, Hidekuni
N1 - Publisher Copyright:
Copyright © The Author(s) 2019.
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Background Pregnant women require increased levels of n-3 polyunsaturated fatty acids (PUFAs) due to the demands of the growing fetus. Although some evidence indicates that maternal intake of fish and n-3 PUFAs is associated with reduced risk of postpartum depression, the results are inconsistent. Methods We investigated whether dietary consumption of fish and/or n-3 PUFAs during pregnancy is associated with a reduced risk of maternal postpartum depression at 6 months after delivery and of serious mental illness at 1 year in a Japanese population. After exclusion and multiple imputation from a dataset comprising 103 062 pregnancies obtained in the Japan Environment and Children's Study, we evaluated 84 181 and 81 924 women at 6 months and 1 year after delivery, respectively. Results Multivariable logistic regression showed a reduced risk of postpartum depression at 6 months in the second to fifth quintiles v. the lowest quintile for fish and n-3 PUFA intake, with trend tests also revealing a significant linear association. At 1 year after delivery, fish intake was associated with a reduced risk of serious mental illness in the second to fifth quintiles v. the lowest quintile for fish and in the third to fifth quintiles v. the lowest quintile for n-3 PUFA intake, with trend tests also revealing a significant linear association. Conclusions Women with higher fish and/or n-3 PUFA intake showed reduced risk of postpartum depression at 6 months after delivery and of serious mental illness at 1 year after delivery.
AB - Background Pregnant women require increased levels of n-3 polyunsaturated fatty acids (PUFAs) due to the demands of the growing fetus. Although some evidence indicates that maternal intake of fish and n-3 PUFAs is associated with reduced risk of postpartum depression, the results are inconsistent. Methods We investigated whether dietary consumption of fish and/or n-3 PUFAs during pregnancy is associated with a reduced risk of maternal postpartum depression at 6 months after delivery and of serious mental illness at 1 year in a Japanese population. After exclusion and multiple imputation from a dataset comprising 103 062 pregnancies obtained in the Japan Environment and Children's Study, we evaluated 84 181 and 81 924 women at 6 months and 1 year after delivery, respectively. Results Multivariable logistic regression showed a reduced risk of postpartum depression at 6 months in the second to fifth quintiles v. the lowest quintile for fish and n-3 PUFA intake, with trend tests also revealing a significant linear association. At 1 year after delivery, fish intake was associated with a reduced risk of serious mental illness in the second to fifth quintiles v. the lowest quintile for fish and in the third to fifth quintiles v. the lowest quintile for n-3 PUFA intake, with trend tests also revealing a significant linear association. Conclusions Women with higher fish and/or n-3 PUFA intake showed reduced risk of postpartum depression at 6 months after delivery and of serious mental illness at 1 year after delivery.
KW - Fish intake
KW - n-3 polyunsaturated fatty acids
KW - postpartum depression
KW - pregnancy
KW - serious mental illness
UR - http://www.scopus.com/inward/record.url?scp=85072525600&partnerID=8YFLogxK
U2 - 10.1017/S0033291719002587
DO - 10.1017/S0033291719002587
M3 - 学術論文
C2 - 31535610
AN - SCOPUS:85072525600
SN - 0033-2917
VL - 50
SP - 2416
EP - 2424
JO - Psychological Medicine
JF - Psychological Medicine
IS - 14
ER -