Dietary intake of fish and n-3 polyunsaturated fatty acids and risk of postpartum depression: A nationwide longitudinal study - The Japan Environment and Children's Study (JECS)

Kei Hamazaki*, Kenta Matsumura, Akiko Tsuchida, Haruka Kasamatsu, Tomomi Tanaka, Mika Ito, Hidekuni Inadera

*この論文の責任著者

研究成果: ジャーナルへの寄稿学術論文査読

29 被引用数 (Scopus)

抄録

Background Pregnant women require increased levels of n-3 polyunsaturated fatty acids (PUFAs) due to the demands of the growing fetus. Although some evidence indicates that maternal intake of fish and n-3 PUFAs is associated with reduced risk of postpartum depression, the results are inconsistent. Methods We investigated whether dietary consumption of fish and/or n-3 PUFAs during pregnancy is associated with a reduced risk of maternal postpartum depression at 6 months after delivery and of serious mental illness at 1 year in a Japanese population. After exclusion and multiple imputation from a dataset comprising 103 062 pregnancies obtained in the Japan Environment and Children's Study, we evaluated 84 181 and 81 924 women at 6 months and 1 year after delivery, respectively. Results Multivariable logistic regression showed a reduced risk of postpartum depression at 6 months in the second to fifth quintiles v. the lowest quintile for fish and n-3 PUFA intake, with trend tests also revealing a significant linear association. At 1 year after delivery, fish intake was associated with a reduced risk of serious mental illness in the second to fifth quintiles v. the lowest quintile for fish and in the third to fifth quintiles v. the lowest quintile for n-3 PUFA intake, with trend tests also revealing a significant linear association. Conclusions Women with higher fish and/or n-3 PUFA intake showed reduced risk of postpartum depression at 6 months after delivery and of serious mental illness at 1 year after delivery.

本文言語英語
ページ(範囲)2416-2424
ページ数9
ジャーナルPsychological Medicine
50
14
DOI
出版ステータス出版済み - 2020/10/01

ASJC Scopus 主題領域

  • 応用心理学
  • 精神医学および精神衛生

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