Contemporary optimal therapeutic strategy with escalation/de-escalation of temporary mechanical circulatory support in patients with cardiogenic shock and advanced heart failure in Japan

Makiko Nakamura, Teruhiko Imamura*, Kinugawa Koichiro

*この論文の責任著者

研究成果: ジャーナルへの寄稿総説査読

1 被引用数 (Scopus)

抄録

The utilization of temporary mechanical circulatory support (MCS) in the management of cardiogenic shock is experiencing a notable surge. Acute myocardial infarction remains the predominant etiology of cardiogenic shock, followed by heart failure. Recent findings from the DanGer Shock trial indicate that the percutaneous micro-axial flow pump support, in conjunction with standard care, significantly reduced 6-month mortality in patients with acute myocardial infarction-related cardiogenic shock compared to those receiving standard care alone. However, real-world registry data reveal that the 30-day mortality among patients with acute myocardial infarction-related cardiogenic shock, who received concomitant veno-arterial extracorporeal membrane oxygenation support along with micro-axial flow pump, remain suboptimal. The persistent challenge in the field is how to incorporate, escalate, and de-escalate these temporary MCS to further improve clinical outcomes in such clinical scenarios. This review aims to elucidate the current practices surrounding the escalation and de-escalation of temporary MCS in real-world clinical settings and proposes considerations for future advancements in this critical area.

本文言語英語
論文番号e007924
ページ(範囲)103-109
ページ数7
ジャーナルJournal of Artificial Organs
28
2
DOI
出版ステータス出版済み - 2025/06

ASJC Scopus 主題領域

  • 医学(その他)
  • 生体材料
  • 生体医工学
  • 循環器および心血管医学

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