Cloning of human anti-factor XIII monoclonal antibody dissects mechanisms of polyclonal antibodies in a single patient

Keyphrases

• Monoclonal Antibody 100%
• Autoantibodies 100%
• Dissociation 100%
• Polyclonal Antibody 100%
• Single Patient 100%
• Assembly Inhibitor 80%
• Factor XIIIa 60%
• Non-neutralizing 40%
• Older Men 20%
• Pathophysiology 20%
• Peripheral Blood 20%
• Complementary DNA (cDNA) 20%
• Thrombin 20%
• Anticoagulants 20%
• 3-group 20%
• Strong Inhibition 20%
• Autoimmune 20%
• β Subunit 20%
• Ca2+ Dependence 20%
• Inhibitory Mechanism 20%
• Fibrin 20%
• Amine Incorporation 20%
• Non-neutralizing Antibodies 20%
• Peptide Cleavage 20%
• Coagulation Factor XIII 20%
• Acquired Factor XIII Deficiency 20%
• Patient Plasma 20%
• Abnormal Bleeding 20%
• DNA Cloning 20%
• Lethal Bleeding 20%
• Activation Peptide 20%
• B-factor 20%
• Fibrin Thrombi 20%
• Cloning Method 20%

Immunology and Microbiology

• Monoclonal Antibody 100%
• Autoantibodies 100%
• Polyclonal Antibody 100%
• Human Monoclonal Antibody 80%
• Blood Plasma 40%
• Cross Linking 40%
• Molecular Cloning 20%
• Fibrin Clot 20%
• Immunology 20%
• Thrombin 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Monoclonal Antibody 100%
• Blood Clotting Factor 13 100%
• Polyclonal Antibody 100%
• Autoantibodies 27%
• Human Monoclonal Antibody 22%
• Bleeding 11%
• Heterodimer 5%
• Calcium Ion 5%
• Complementary DNA 5%
• Anticoagulant Agent 5%
• Thrombin 5%
• Pathophysiology 5%
• Blood Clotting Factor 5%
• Hemostatic Agent 5%
• Thrombus 5%