抄録
Using an in vivo microdialysis technique coupled with HPLC-fluorometry, the release of neuronal histamine from the anterior hypothalamic area was monitored continuously in conscious, freely moving rats under a 12:12 h light:dark cycle. Spontaneous locomotor activity of the rats was measured simultaneously using a locomotor activity counter. Histamine release gradually increased in the second half of the light period (1400-2000) and the average histamine release during the dark period (2000-0800, 0.20±0.02 pmol/30 min) was significantly higher than that during the light period (0.12±0.01 pmol/30 min). This clear circadian change in the release suggests that the central histaminergic system is related to the circadian rhythm of rats.
本文言語 | 英語 |
---|---|
ページ(範囲) | 391-394 |
ページ数 | 4 |
ジャーナル | Physiology and Behavior |
巻 | 51 |
号 | 2 |
DOI | |
出版ステータス | 出版済み - 1992/02 |
ASJC Scopus 主題領域
- 実験心理学および認知心理学
- 行動神経科学