TY - CHAP
T1 - Cannabinoids
T2 - Biosynthesis and biotechnological applications
AU - Sirikantaramas, Supaart
AU - Taura, Futoshi
N1 - Publisher Copyright:
© Springer International Publishing AG 2017. All rights reserved.
PY - 2017/5/23
Y1 - 2017/5/23
N2 - Cannabinoids are unique terpenophenolic metabolites found only in Cannabis sativa. The biosynthetic mechanism of these compounds had long been ambiguous since conventional biogenetic studies using radiolabelled precursors did not provide definitive results. On the other hand, various enzymological, molecular biological, and omics-based studies conducted over the past two decades have identified the majority of the enzymes and genes involved in the cannabinoid pathway, opening the way to the biotechnological production of pharmacologically active cannabinoids. This chapter describes the history of the biosynthetic studies, in particular those focused on the biosynthetic enzymes, and recent topics linked to cannabinoid-related biotechnology.
AB - Cannabinoids are unique terpenophenolic metabolites found only in Cannabis sativa. The biosynthetic mechanism of these compounds had long been ambiguous since conventional biogenetic studies using radiolabelled precursors did not provide definitive results. On the other hand, various enzymological, molecular biological, and omics-based studies conducted over the past two decades have identified the majority of the enzymes and genes involved in the cannabinoid pathway, opening the way to the biotechnological production of pharmacologically active cannabinoids. This chapter describes the history of the biosynthetic studies, in particular those focused on the biosynthetic enzymes, and recent topics linked to cannabinoid-related biotechnology.
UR - http://www.scopus.com/inward/record.url?scp=85033584218&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-54564-6_8
DO - 10.1007/978-3-319-54564-6_8
M3 - 章
AN - SCOPUS:85033584218
SN - 9783319545639
SP - 183
EP - 206
BT - Cannabis sativa L. - Botany and Biotechnology
PB - Springer International Publishing
ER -