Blood-to-brain influx transport of nicotine at the rat blood-brain barrier: Involvement of a pyrilamine-sensitive organic cation transport process

Keyphrases

• Transport Processes 100%
• Blood-brain Barrier 100%
• Rat Plasma 100%
• Organic Cation Transport 100%
• Nicotine 100%
• Pyrilamine 100%
• Efflux 16%
• Net Flux 16%
• Rat Brain 16%
• Alkaloids 8%
• Brain Capillary Endothelial Cells 8%
• In Vitro Model 8%
• Organic Cation Transporter 8%
• Tobacco 8%
• Neural Response 8%
• Uptake Studies 8%
• Vascular Penetration 8%
• Plot Analysis 8%
• Endothelial Cell Line 8%
• Concentration Dependence 8%
• Major Contributor 8%
• Time-temperature Dependence 8%
• Rat Brain Slices 8%
• Smoking Cessation Intervention 8%
• Km Value 8%
• Indexing Methods 8%
• Integration Plot 8%
• Brain Transport 8%
• Temperature Concentration 8%
• Nicotine Content 8%
• In Vivo Brain 8%
• Blood Clearance 8%

Neuroscience

• Blood Brain Barrier 100%
• Organic Cation Transport 100%
• In Vivo 50%
• In Vitro 16%
• Cell Line 16%
• Nerve Potential 16%
• Brain Slice 16%
• Organic Cation Transporter 16%