抄録
Four new bis-iridoid glycosides, saungmaygaosides A-D (1–4), and six known iridoid glycosides (5–10) were isolated from the n-butanol extract of the stems of Picrorhiza kurroa collected in Myanmar. Their structures were elucidated by extensive spectroscopic techniques. All of the isolates were assayed for anti-Vpr activity, using TREx-HeLa-Vpr cells. Among the isolates, saungmaygaoside D (4), sylvestroside IV dimethyl acetal (7), and sweroside (8) were the most potent inhibitors with effective doses of 5 and 10 μM, respectively, without showing any notable cytotoxicities.
本文言語 | 英語 |
---|---|
ページ(範囲) | 101-107 |
ページ数 | 7 |
ジャーナル | Fitoterapia |
巻 | 134 |
DOI | |
出版ステータス | 出版済み - 2019/04 |
ASJC Scopus 主題領域
- 薬理学
- 創薬