抄録
An asymmetric total synthesis of (-)-trans-blechnic acid, a dihydrobenzofuran neolignan, has been achieved. The key steps involve an elaboration of the cis-2,3-dihydrobenzofuran core structure by enantio- and diastereoselective intramolecular C-H insertion using dirhodium(II) tetrakis[N-phthaloyl-(R)-tert-leucinate] [Rh2(R-PTTL)4] and a direct coupling of an acrylate unit with the core structure employing Yu's palladium(II)-catalyzed intermolecular C-H olefination.
本文言語 | 英語 |
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論文番号 | ST-2013-U0890-L |
ページ(範囲) | 288-292 |
ページ数 | 5 |
ジャーナル | Synlett |
巻 | 25 |
号 | 2 |
DOI | |
出版ステータス | 出版済み - 2014/01 |
ASJC Scopus 主題領域
- 有機化学