Additive-controlled chemoselective inter-/intramolecular hydroamination via electrochemical PCET process

Kazuhiro Okamoto, Naoki Shida, Mahito Atobe

研究成果: ジャーナルへの寄稿学術論文査読

2 被引用数 (Scopus)

抄録

Electrochemically generated amidyl radical species produced distinct inter- or intramolecular hydroamination reaction products via a proton-coupled electron transfer (PCET) mechanism. Cyclic voltammetry (CV) analysis indicated that the chemoselectivity was derived from the size of the hydrogen bond complex, which consisted of the carbamate substrate and phosphate base, and could be controlled using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as an additive. These results provide fundamental insights for the design of PCET-based redox reaction systems under electrochemical conditions.
寄稿の翻訳タイトルAdditive-controlled chemoselective inter-/intramolecular hydroamination via electrochemical PCET process
本文言語英語
ページ(範囲)264-271
ページ数8
ジャーナルBeilstein Journal of Organic Chemistry
20
DOI
出版ステータス出版済み - 2024/02/12
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