抄録
Electrochemically generated amidyl radical species produced distinct inter- or intramolecular hydroamination reaction products via a proton-coupled electron transfer (PCET) mechanism. Cyclic voltammetry (CV) analysis indicated that the chemoselectivity was derived from the size of the hydrogen bond complex, which consisted of the carbamate substrate and phosphate base, and could be controlled using 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as an additive. These results provide fundamental insights for the design of PCET-based redox reaction systems under electrochemical conditions.
寄稿の翻訳タイトル | Additive-controlled chemoselective inter-/intramolecular hydroamination via electrochemical PCET process |
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本文言語 | 英語 |
ページ(範囲) | 264-271 |
ページ数 | 8 |
ジャーナル | Beilstein Journal of Organic Chemistry |
巻 | 20 |
DOI | |
出版ステータス | 出版済み - 2024/02/12 |
外部発表 | はい |