A590T mutation in KCNQ1 C-terminal helix D decreases I_Ks channel trafficking and function but not Yotiao interaction

Koshi Kinoshita, Takuto Komatsu, Kohki Nishide, Yukiko Hata, Nozomi Hisajima, Hiroyuki Takahashi, Katsuya Kimoto, Kei Aonuma, Eikichi Tsushima, Toshihide Tabata, Tomoyuki Yoshida, Hisashi Mori, Kunihiro Nishida, Yoshiaki Yamaguchi, Fukiko Ichida, Kenkichi Fukurotani, Hiroshi Inoue, Naoki Nishida^*