@article{47541b8568184d9d8667fa64bc43aeee,
title = "A new entry to asymmetric synthesis of 1-substituted 1,2,3,4-tetrahydro-β-carbolines employing a pyroglutamic acid derivative as a chiral auxiliary",
abstract = "β-Carboline which was protected at N-9 by an acyl group derived from L-pyroglutamic acid reacted with allyltributyltin or silyl enol ethers in the presence of an alkyl chloroformate in a highly diastereoselective manner to give 1-substituted 1,2-dihydro-β-carbolines. The compounds were readily transformed to the corresponding asymmetric 1-substituted tetrahydro-β-carbolines that are common partial structures in a variety of indole alkaloids.",
keywords = "Allyltributyltin, Asymmetric addition, Indole alkaloid, Pyroglutamic acid, Silyl enol ether, β-carboline",
author = "Takashi Itoh and Kazuhiro Nagata and Masashi Yokoya and Michiko Miyazaki and Sachiko Ikeda and Yuji Matsuya and Yasuko Enomoto and Akio Ohsawa",
year = "2002",
doi = "10.1055/s-2002-31931",
language = "英語",
pages = "1005--1007",
journal = "Synlett",
issn = "0936-5214",
publisher = "Georg Thieme Verlag",
number = "6",
}