A Case of Primary Somatostatin-Producing Tumor of the Duodenum with Liver Metastases with Long-Term Survival of More than 20 Years

Jungo Yoshida, Yuto Kitano, Tomoya Tsukada, Masahide Kaji, Tatsuhiro Araki, Hiroaki Horio, Kenta Sukegawa, Toru Kurata, Atsushi Hirose, Masahiro Hada, Koji Amaya, Akemi Yoshikawa, Kiichi Maeda

研究成果: ジャーナルへの寄稿学術論文査読

抄録

A 52-year-old woman underwent esophagogastroduodenoscopy after an abnormal medical examination, which revealed a mass lesion over half the circumference of the superior duodenal angulus. Immunostaining was diffusely positive for somatostatin, synaptophysin, and chromogranin A. A 3 cm-sized mass in the pancreaticoduodenal region and multiple nodular lesions of a few mm in both lobes of the liver were revealed by CT. The diagnosis is primary somatostatin-producing tumor of the duodenum with multiple liver metastases. She underwent gastric jejunal bypass for impaired transit. Afterwards hepatic infusion and systemic chemotherapy were continued, and 5 years passed without progression. When she stopped chemotherapy for 6 months, she started somatostatin analogue therapy because of the increase of the tumors. The tumors did not increase, and 20 years have passed since the start of treatment. We report a case of primary somatostatin-producing tumor of the duodenum with liver metastases that is still alive for a long period of time, with a review of the literature.

本文言語英語
ページ(範囲)1881-1883
ページ数3
ジャーナルJapanese Journal of Cancer and Chemotherapy
50
13
出版ステータス出版済み - 2023/12/01

ASJC Scopus 主題領域

  • 医学一般

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