胃腺癌化学療法中に原発巣増大をきたし混合型腺神経内分泌腫瘍と診断した 1 例

Mayo Fuchino*, Atsuko Nakaya, Takayuki Ando, Yuushi Hasumoto, Koji Ozawa, Hiroyuki Ito, Kazuhisa Yabushita, Shigeharu Miwa, Shinichi Hayashi

*この論文の責任著者

研究成果: ジャーナルへの寄稿学術論文査読

抄録

Gastric mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) is an extremely rare form of gastric neoplasm, and its prognosis is often poor. This is a case report wherein the primary site increased during chemotherapy against gastric adenocarcinoma and was diagnosed with gastric MiNEN after total gastrectomy. A 71-year-old man was diagnosed with gastric adenocarcinoma complicated with liver and para-aortic lymph node metastasis. Chemotherapy with S-1, oxaliplatin, and trastuzumab was initiated. Although the size of metastatic lesions was reduced after six courses of treatment, a part of the primary site of gastric tumor rapidly. Pathological rebiopsy of the primary site suggested a neuroendocrine carcinoma, and he was finally diagnosed with gastric MiNEN after total gastrectomy. Thus, second-line chemotherapy was then initiated showing good response. We herein report a case of MiNEN with a rare diagnostic process.

寄稿の翻訳タイトルA case of mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) diagnosed by re-biopsy of the enlarged primary tumor during chemotherapy for gastric adenocarcinoma
本文言語日本
ページ(範囲)55-62
ページ数8
ジャーナルJournal of Japanese Society of Gastroenterology
121
1
DOI
出版ステータス出版済み - 2024

ASJC Scopus 主題領域

  • 消化器病学

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