TY - JOUR
T1 - Visualization of Lenticulostriate Arteries at 3T
T2 - Optimization of Slice-selective Off-resonance Sinc Pulse-prepared TOF-MRA and Its Comparison with Flow-sensitive Black-blood MRA
AU - Okuchi, Sachi
AU - Okada, Tomohisa
AU - Fujimoto, Koji
AU - Fushimi, Yasutaka
AU - Kido, Aki
AU - Yamamoto, Akira
AU - Kanagaki, Mitsunori
AU - Dodo, Toshiki
AU - Mehemed, Taha M.
AU - Miyazaki, Mitsue
AU - Zhou, Xiangzhi
AU - Togashi, Kaori
N1 - Funding Information:
Grants : This work is funded by a sponsored research program “Research for Improvement of MR Visualization (No. 150100700014 )” of Toshiba Medical Systems , Japan, and Grant-in-Aid for Scientific Research on Innovative Areas “Initiative for High-Dimensional Data-Driven Science through Deepening of Sparse Modeling (No. 4503 )” of The Ministry of Education, Culture, Sports, Science and Technology , Japan provided to K.T. The former grant contributed to the acquisition of volunteer images of TOF-MRA and FSBB-MRA. The latter grant contributed to analysis of the acquired data.
PY - 2014/6
Y1 - 2014/6
N2 - Rationale and Objectives: To optimize visualization of lenticulostriate artery (LSA) by time-of-flight (TOF) magnetic resonance angiography (MRA) with slice-selective off-resonance sinc (SORS) saturation transfer contrast pulses and to compare capability of optimal TOF-MRA and flow-sensitive black-blood (FSBB) MRA to visualize the LSA at 3T. Materials and Methods: This study was approved by the local ethics committee, and written informed consent was obtained from all the subjects. TOF-MRA was optimized in 20 subjects by comparing SORS pulses of different flip angles: 0, 400°, and 750°. Numbers of LSAs were counted. The optimal TOF-MRA was compared to FSBB-MRA in 21 subjects. Images were evaluated by the numbers and length of visualized LSAs. Results: LSAs were significantly more visualized in TOF-MRA with SORS pulses of 400° than others (P < .003). When the optimal TOF-MRA was compared to FSBB-MRA, the visualization of LSA using FSBB (mean branch numbers 11.1, 95% confidence interval (CI) 10.0-12.1; mean total length 236 mm, 95% CI 210-263 mm) was significantly better than using TOF (4.7, 95% CI 4.1-5.3; 78 mm, 95% CI 67-89 mm) for both numbers and length of the LSA (P < .0001). Conclusions: LSA visualization was best with 400° SORS pulses for TOF-MRA but FSBB-MRA was better than TOF-MRA, which indicates its clinical potential to investigate the LSA on a 3T magnetic resonance imaging.
AB - Rationale and Objectives: To optimize visualization of lenticulostriate artery (LSA) by time-of-flight (TOF) magnetic resonance angiography (MRA) with slice-selective off-resonance sinc (SORS) saturation transfer contrast pulses and to compare capability of optimal TOF-MRA and flow-sensitive black-blood (FSBB) MRA to visualize the LSA at 3T. Materials and Methods: This study was approved by the local ethics committee, and written informed consent was obtained from all the subjects. TOF-MRA was optimized in 20 subjects by comparing SORS pulses of different flip angles: 0, 400°, and 750°. Numbers of LSAs were counted. The optimal TOF-MRA was compared to FSBB-MRA in 21 subjects. Images were evaluated by the numbers and length of visualized LSAs. Results: LSAs were significantly more visualized in TOF-MRA with SORS pulses of 400° than others (P < .003). When the optimal TOF-MRA was compared to FSBB-MRA, the visualization of LSA using FSBB (mean branch numbers 11.1, 95% confidence interval (CI) 10.0-12.1; mean total length 236 mm, 95% CI 210-263 mm) was significantly better than using TOF (4.7, 95% CI 4.1-5.3; 78 mm, 95% CI 67-89 mm) for both numbers and length of the LSA (P < .0001). Conclusions: LSA visualization was best with 400° SORS pulses for TOF-MRA but FSBB-MRA was better than TOF-MRA, which indicates its clinical potential to investigate the LSA on a 3T magnetic resonance imaging.
KW - Flow-sensitive black-blood
KW - Lenticulostriate artery
KW - MR angiography
KW - Saturation transfer contrast
KW - Slice-selective off-resonance sinc pulse
UR - http://www.scopus.com/inward/record.url?scp=84899867725&partnerID=8YFLogxK
U2 - 10.1016/j.acra.2014.03.007
DO - 10.1016/j.acra.2014.03.007
M3 - 学術論文
C2 - 24809322
AN - SCOPUS:84899867725
SN - 1076-6332
VL - 21
SP - 812
EP - 816
JO - Academic Radiology
JF - Academic Radiology
IS - 6
ER -