Versatile synthesis of fluorescent, cross-linked peptides as biological probes with the advantage of high helix content

Kazuhisa Fujimoto*, Masaoki Kajino, Masahiko Inouye

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A variety of fluorophores were introduced at the N-termini of short peptides for use as biological-probes. The fluorescent peptides were cross-linked with a diacetylenic cross-linking agent between the amino acid side chains of ornithine (Orn) residues to produce peptides with high helix content.

Original languageEnglish
Pages (from-to)311-319
Number of pages9
JournalResearch on Chemical Intermediates
Volume39
Issue number1
DOIs
StatePublished - 2013/01

Keywords

  • Biological probe
  • Fluorescence labeling
  • Fluorophore
  • Short helical peptide

ASJC Scopus subject areas

  • General Chemistry

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