Uterine Peristalsis in Women With Repeated IVF Failures: Possible Therapeutic Effect of Hyoscine Bromide

Aki Kido; Kaori Togashi; Hiroshi Hatayama; Takahiro Nakayama; Akira Yamamoto; Masako Kataoka; Togas Tulandi

doi:10.1016/S1701-2163(16)34278-5

Uterine Peristalsis in Women With Repeated IVF Failures: Possible Therapeutic Effect of Hyoscine Bromide

Aki Kido, Kaori Togashi, Hiroshi Hatayama, Takahiro Nakayama, Akira Yamamoto, Masako Kataoka, Togas Tulandi

Diagnostic and Therapeutic Radiology

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Background: Uterine peristalsis, which is influenced by hormonal and cholinergic effects, may have a role in successful implantation and continuing pregnancy. Cases: We encountered abnormal uterine peristalsis in three women who had had repeated in vitro fertilization (IVF) treatment failures. They subsequently had successful pregnancies when hyoscine bromide was administered at the time of embryo transfer. Conclusion: It is possible that decreasing uterine peristalsis with use of an anticholinergic agent during IVF treatment facilitates retention of embryos and increases the probability of successful pregnancy.

Original language	English
Pages (from-to)	732-735
Number of pages	4
Journal	Journal of Obstetrics and Gynaecology Canada
Volume	31
Issue number	8
DOIs	https://doi.org/10.1016/S1701-2163(16)34278-5
State	Published - 2009

Keywords

Anti-cholinergic agent
Hyoscine
Infertility
MRI
Uterine peristalsis

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1016/S1701-2163(16)34278-5

Cite this

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title = "Uterine Peristalsis in Women With Repeated IVF Failures: Possible Therapeutic Effect of Hyoscine Bromide",

abstract = "Background: Uterine peristalsis, which is influenced by hormonal and cholinergic effects, may have a role in successful implantation and continuing pregnancy. Cases: We encountered abnormal uterine peristalsis in three women who had had repeated in vitro fertilization (IVF) treatment failures. They subsequently had successful pregnancies when hyoscine bromide was administered at the time of embryo transfer. Conclusion: It is possible that decreasing uterine peristalsis with use of an anticholinergic agent during IVF treatment facilitates retention of embryos and increases the probability of successful pregnancy.",

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author = "Aki Kido and Kaori Togashi and Hiroshi Hatayama and Takahiro Nakayama and Akira Yamamoto and Masako Kataoka and Togas Tulandi",

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T1 - Uterine Peristalsis in Women With Repeated IVF Failures

T2 - Possible Therapeutic Effect of Hyoscine Bromide

AU - Kido, Aki

AU - Togashi, Kaori

AU - Hatayama, Hiroshi

AU - Nakayama, Takahiro

AU - Yamamoto, Akira

AU - Kataoka, Masako

AU - Tulandi, Togas

PY - 2009

Y1 - 2009

N2 - Background: Uterine peristalsis, which is influenced by hormonal and cholinergic effects, may have a role in successful implantation and continuing pregnancy. Cases: We encountered abnormal uterine peristalsis in three women who had had repeated in vitro fertilization (IVF) treatment failures. They subsequently had successful pregnancies when hyoscine bromide was administered at the time of embryo transfer. Conclusion: It is possible that decreasing uterine peristalsis with use of an anticholinergic agent during IVF treatment facilitates retention of embryos and increases the probability of successful pregnancy.

AB - Background: Uterine peristalsis, which is influenced by hormonal and cholinergic effects, may have a role in successful implantation and continuing pregnancy. Cases: We encountered abnormal uterine peristalsis in three women who had had repeated in vitro fertilization (IVF) treatment failures. They subsequently had successful pregnancies when hyoscine bromide was administered at the time of embryo transfer. Conclusion: It is possible that decreasing uterine peristalsis with use of an anticholinergic agent during IVF treatment facilitates retention of embryos and increases the probability of successful pregnancy.

KW - Anti-cholinergic agent

KW - Hyoscine

KW - Infertility

KW - MRI

KW - Uterine peristalsis

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Uterine Peristalsis in Women With Repeated IVF Failures: Possible Therapeutic Effect of Hyoscine Bromide

Abstract

Keywords

ASJC Scopus subject areas

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