Usefulness of novel imaging modalities in diagnosis of focal nodular hyperplasia of the liver

Yohichi Nishigaki*, Eiichi Tomita, Yoshihiko Matsuno, Ken Goto, Takaya Ohnishi, Yuji Tanaka, Hiroko Iwai, Hisao Asano, Ichiro Yasuda, Kazuo Nagura, Tatsuo Wakahara, Tetsuta Yamada

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A 17-year-old woman was admitted because of a liver tumor found incidentally by ultrasonography. Liver function was normal and there were no markers of hepatitis viruses or malignancy. Abdominal ultrasonography, computed tomography (CT), and magnetic resonance imaging revealed a mass (2cm in diameter) in the lateral segment of the left lobe of the liver. The lesion was not detected by hepatic arteriography. However, dynamic CT with fast scanning and dynamic CO2-enhanced ultrasonography demonstrated initial central enhancement of the mass followed by centrifugal spread of enhancement to the periphery. Color Doppler flow imaging detected a central color spot, shown to be an artery by a pulsed Doppler spectrum analysis. Fine-needle biopsy confirmed a diagnosis of focal nodular hyperplasia. Dynamic CT with fast scanning, dynamic CO2-enhanced ultrasonography, and color Doppler flow imaging were useful in detecting the vascular pattern specific to focal nodular hyperplasia. Investigation of further cases with these novel imaging modalities should help to establish a comprehensive diagnostic procedure and thus avoid unnecessary surgery for focal nodular hyperplasia, which is a completely benign lesion.

Original languageEnglish
Pages (from-to)677-683
Number of pages7
JournalJournal of Gastroenterology
Volume32
Issue number5
DOIs
StatePublished - 1997/10

Keywords

  • Dynamic CO-enhanced ultrasonography
  • Dynamic CT
  • Focal nodular hyperplasia

ASJC Scopus subject areas

  • Gastroenterology

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