Total synthesis of sphingofungin E and 4,5-di-epi-sphingofungin E

Narumi Noda, Hisanori Nambu, Tomoya Fujiwara, Takayuki Yakura*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Total synthesis of sphingofungin E and 4,5-di-epi-sphingofungin E was achieved from an intermediate same as that of myriocin and mycestericin D via antipodal stereoselective dihydroxylations.

Original languageEnglish
Pages (from-to)687-696
Number of pages10
JournalChemical and Pharmaceutical Bulletin
Volume65
Issue number7
DOIs
StatePublished - 2017

Keywords

  • Dihydroxylation
  • Osmium tetroxide
  • Sphingofungin E
  • Stereoselectivity
  • Total synthesis

ASJC Scopus subject areas

  • General Chemistry
  • Drug Discovery

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