Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain

Hiroaki Saito; Etsuko Yuri; Masahiro Miyazawa; Yasuhiro Itagaki; Terumi Nakajima; Masaaki Miyashita

doi:10.1016/S0040-4039(98)01379-3

Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain

Hiroaki Saito, Etsuko Yuri, Masahiro Miyazawa, Yasuhiro Itagaki, Terumi Nakajima, Masaaki Miyashita^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The first total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a 4-hydroxyindole nucleus and a unique putreanine trimer and tetramer acylpolyamine chain, respectively, has been achieved by the iterative use of a key azide compound.

Original language	English
Pages (from-to)	6479-6482
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	36
DOIs	https://doi.org/10.1016/S0040-4039(98)01379-3
State	Published - 1998/09

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain",

abstract = "The first total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a 4-hydroxyindole nucleus and a unique putreanine trimer and tetramer acylpolyamine chain, respectively, has been achieved by the iterative use of a key azide compound.",

author = "Hiroaki Saito and Etsuko Yuri and Masahiro Miyazawa and Yasuhiro Itagaki and Terumi Nakajima and Masaaki Miyashita",

year = "1998",

month = sep,

doi = "10.1016/S0040-4039(98)01379-3",

language = "英語",

volume = "39",

pages = "6479--6482",

journal = "Tetrahedron Letters",

issn = "0040-4039",

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T1 - Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain

AU - Saito, Hiroaki

AU - Yuri, Etsuko

AU - Miyazawa, Masahiro

AU - Itagaki, Yasuhiro

AU - Nakajima, Terumi

AU - Miyashita, Masaaki

PY - 1998/9

Y1 - 1998/9

N2 - The first total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a 4-hydroxyindole nucleus and a unique putreanine trimer and tetramer acylpolyamine chain, respectively, has been achieved by the iterative use of a key azide compound.

AB - The first total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a 4-hydroxyindole nucleus and a unique putreanine trimer and tetramer acylpolyamine chain, respectively, has been achieved by the iterative use of a key azide compound.

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U2 - 10.1016/S0040-4039(98)01379-3

DO - 10.1016/S0040-4039(98)01379-3

M3 - 学術論文

AN - SCOPUS:0032171333

SN - 0040-4039

VL - 39

SP - 6479

EP - 6482

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 36

ER -

Total synthesis of NPTX-5 and NPTX-6, Joro spider (Nephila clavata) toxins having a unique putreanine trimer and putreanine tetramer acylpolyamine chain

Abstract

ASJC Scopus subject areas

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