Total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus

Masaaki Miyashita; Hiroaki Saito; Masayuki Matsushita; Masahiro Miyazawa; Yasuhiro Itagaki; Terumi Nakajima

doi:10.1016/S0040-4039(97)10205-2

Total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus

Masaaki Miyashita^*, Hiroaki Saito, Masayuki Matsushita, Masahiro Miyazawa, Yasuhiro Itagaki, Terumi Nakajima

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The first total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus, has been achieved by using two key azide intermediates.

Original language	English
Pages (from-to)	8297-8298
Number of pages	2
Journal	Tetrahedron Letters
Volume	38
Issue number	48
DOIs	https://doi.org/10.1016/S0040-4039(97)10205-2
State	Published - 1997/12/01

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(97)10205-2

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title = "Total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus",

abstract = "The first total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus, has been achieved by using two key azide intermediates.",

author = "Masaaki Miyashita and Hiroaki Saito and Masayuki Matsushita and Masahiro Miyazawa and Yasuhiro Itagaki and Terumi Nakajima",

year = "1997",

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doi = "10.1016/S0040-4039(97)10205-2",

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T1 - Total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus

AU - Miyashita, Masaaki

AU - Saito, Hiroaki

AU - Matsushita, Masayuki

AU - Miyazawa, Masahiro

AU - Itagaki, Yasuhiro

AU - Nakajima, Terumi

PY - 1997/12/1

Y1 - 1997/12/1

N2 - The first total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus, has been achieved by using two key azide intermediates.

AB - The first total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus, has been achieved by using two key azide intermediates.

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U2 - 10.1016/S0040-4039(97)10205-2

DO - 10.1016/S0040-4039(97)10205-2

M3 - 学術論文

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SN - 0040-4039

VL - 38

SP - 8297

EP - 8298

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 48

ER -

Total synthesis of Nephilatoxin-1 (NPTX-1), a Joro spider (Nephila clavata) toxin having a 4-hydroxyindole nucleus

Abstract

ASJC Scopus subject areas

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