TY - JOUR
T1 - Third epidemiological analysis of nasopharyngeal carcinoma in the central region of japan from 2006 to 2015
AU - Kanno, Masafumi
AU - Narita, Norihiko
AU - Fujimoto, Yasushi
AU - Wakisaka, Naohiro
AU - Yoshizaki, Tomokazu
AU - Kodaira, Takeshi
AU - Makita, Chiyoko
AU - Sato, Yuichiro
AU - Yamazaki, Keisuke
AU - Wakaoka, Takanori
AU - Shimode, Yuzo
AU - Tsuji, Hiroyuki
AU - Kito, Ryosuke
AU - Ishinaga, Hajime
AU - Hosokawa, Seiji
AU - Takakura, Hiromasa
AU - Nishimura, Kunihiro
AU - Matoba, Takuma
AU - Fujieda, Shigeharu
N1 - Publisher Copyright:
© 2019 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2019/8
Y1 - 2019/8
N2 - The present study aimed to clarify the incidence and clinical outcomes of nasopharyngeal carcinoma (NPC) in the Chubu region of Japan from 2006 to 2015, compared with previous reports. A retrospective analysis was conducted based on medical records from 40 hospitals located in the Chubu region in the central Japanese main island, with a population of around 22.66 million individuals. This study was designed in line with to two previous clinical studies into NPC conducted in the same area of Japan. We recruited NPC patients diagnosed in hospitals across this area over a 10-year period (2006–2015) using a questionnaire about sex, age, primary site, clinical symptoms, pathology, Union for International Cancer Control (UICC) staging, serological exam, treatment, and survival. A total of 620 NPC patients were identified. The age-standardized incidence of NPC from 2006 to 2015 was 0.27 per 100,000 individuals per year. There were no significant differences between this study and the previous two studies conducted in the same area of Japan. The five-year overall survival rate for all patients was 75.9%, while those for patients with stages I, II, III, and IVA were 97%, 91%, 79%, and 68%, respectively. The age-standardized annual incidence of NPC in the present study was 0.27 per 100,000 individuals per year, which was relatively low and stable. The five-year overall survival rate for all NPC patients was significantly improved in this decade compared with previous studies. The smoking rates in male and female NPC patients were 64.5% and 18.8%, respectively, thereby suggesting the involvement of smoking in the incidence of NPC.
AB - The present study aimed to clarify the incidence and clinical outcomes of nasopharyngeal carcinoma (NPC) in the Chubu region of Japan from 2006 to 2015, compared with previous reports. A retrospective analysis was conducted based on medical records from 40 hospitals located in the Chubu region in the central Japanese main island, with a population of around 22.66 million individuals. This study was designed in line with to two previous clinical studies into NPC conducted in the same area of Japan. We recruited NPC patients diagnosed in hospitals across this area over a 10-year period (2006–2015) using a questionnaire about sex, age, primary site, clinical symptoms, pathology, Union for International Cancer Control (UICC) staging, serological exam, treatment, and survival. A total of 620 NPC patients were identified. The age-standardized incidence of NPC from 2006 to 2015 was 0.27 per 100,000 individuals per year. There were no significant differences between this study and the previous two studies conducted in the same area of Japan. The five-year overall survival rate for all patients was 75.9%, while those for patients with stages I, II, III, and IVA were 97%, 91%, 79%, and 68%, respectively. The age-standardized annual incidence of NPC in the present study was 0.27 per 100,000 individuals per year, which was relatively low and stable. The five-year overall survival rate for all NPC patients was significantly improved in this decade compared with previous studies. The smoking rates in male and female NPC patients were 64.5% and 18.8%, respectively, thereby suggesting the involvement of smoking in the incidence of NPC.
KW - Incidence
KW - Japan
KW - Nasopharyngeal carcinoma (NPC)
KW - Survival
UR - http://www.scopus.com/inward/record.url?scp=85071764176&partnerID=8YFLogxK
U2 - 10.3390/cancers11081180
DO - 10.3390/cancers11081180
M3 - 学術論文
AN - SCOPUS:85071764176
SN - 2072-6694
VL - 11
JO - Cancers
JF - Cancers
IS - 8
M1 - 1180
ER -