Thioarylation of 6-Amino-2,3,6-trideoxy-d-manno-oct-2-ulosonic Acid (IminoKdo): Access to 3,6-Disubstituted Picolinates and Mechanistic Insights

Keyphrases

• Disubstituted 100%
• Amino 100%
• Mechanistic Insight 100%
• OCT2 100%
• Picolinate 100%
• Thioarylation 100%
• Ulosonic Acids 100%
• 31P NMR 50%
• NMR Analysis 50%
• Regioselectivity 50%
• Good Yield 50%
• Stereoselectivity 50%
• Active Species 50%
• Electron-rich 50%
• Reaction Mechanism 50%
• Aromatization 50%
• Time-lapse 50%
• Disulfide 50%
• Electron-deficient 50%
• Enamines 50%
• Azido 50%
• Nucleophilic Attack 50%
• Ketoesters 50%
• Regio 50%
• Storks 50%
• Coupling Products 50%
• Acid-promoted 50%
• Staudinger-aza-Wittig Reaction 50%
• Aryl Thiols 50%
• Metal-free Coupling 50%
• Amine-imine 50%

Chemistry

• Enamine 100%
• NMR Spectroscopy 50%
• Disulfide 50%
• Aza-Wittig Reaction 50%
• formation 50%
• Imine 50%