Therapeutic approaches for chronic hepatitis C: a concise review

Allah Nawaz*, Azhar Manzoor, Saeed Ahmed, Naveed Ahmed, Waseem Abbas, Mushtaq Ahmad Mir, Muhammad Bilal, Alisha Sheikh, Saleem Ahmad, Ishtiaq Jeelani*, Takashi Nakagawa

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

3 Scopus citations

Abstract

Hepatitis C virus (HCV) infection is a significant global health concern, prompting the need for effective treatment strategies. This in-depth review critically assesses the landscape of HCV treatment, drawing parallels between traditional interferon/ribavirin therapy historically pivotal in HCV management and herbal approaches rooted in traditional and complementary medicine. Advancements in therapeutic development and enhanced clinical outcomes axis on a comprehensive understanding of the diverse HCV genome, its natural variations, pathogenesis, and the impact of dietary, social, environmental, and economic factors. A thorough analysis was conducted through reputable sources such as Science Direct, PubMed, Scopus, Web of Science, books, and dissertations. This review primarily focuses on the intricate nature of HCV genomes and explores the potential of botanical drugs in both preventing and treating HCV infections.

Original languageEnglish
Article number1334160
JournalFrontiers in Pharmacology
Volume14
DOIs
StatePublished - 2023

Keywords

  • botanical drugs
  • direct-acting antiviral agents (DAAs)
  • hepatitis C
  • hepatitis C virus
  • hepatoprotective and antiviral properties of medicinal plants

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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