Synthetic hydrogen-bonding receptors for biologically essential monosaccharides

Masahiko Inouye*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Novel macrocyclic saccharide receptors that possess terpyridine skeletons as a hydrogen-bonding site are presented. On modification of the hydrogen-bonding sites and the macrocyclic bridges, the receptors showed selective bindings for ribofuranosides, deoxyribofuranosides, and glucopyranosides, respectively. The binding affinities of the receptors were very high, so that native monosaccharides were solubilized into non-polar solvents in the presence of the receptors. The hydrogen-bonding interactions and the binding modes between them were characterized by 1H NMR spectroscopy.

Original languageEnglish
Pages (from-to)1077-1082
Number of pages6
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Volume58
Issue number11
DOIs
StatePublished - 2000/11

ASJC Scopus subject areas

  • Organic Chemistry

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