Synthesis of various macrosphelides by oxidative derivatization of the macrosphelide core

Yuji Matsuya, Takanori Kawaguchi, Hideo Nemoto*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The macrosphelide core (4), simple 16-membered trilactone, was subjected to several oxidative conditions to produce various natural macrosphelide analogues, including macrosphelides A and C. This approach provided a new access to diverse macrosphelides for a study on their structure-activity relationships.

Original languageEnglish
Pages (from-to)39-43
Number of pages5
JournalHeterocycles
Volume61
DOIs
StatePublished - 2003/12/31

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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