Synthesis of transient functionalized dienes by electrocyclic ring-openingof cyclobutene derivatives

Yuji Matsuya, Kazushige Sasaki, Hideo Nemoto*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Cyclobutenes bearing various functional groups were synthesized by derivatization of squaric acid, and their thermolytic ring-opening reactions were investigated. This sequence was found an effective approach to prepare a multi-functionalized diene, which could be used for subsequent Diels-Alder cycloaddition provided that its s-cis form was fixed.

Original languageEnglish
Pages (from-to)79-92
Number of pages14
JournalArkivoc
Volume2003
Issue number8
StatePublished - 2003

Keywords

  • 1,3-dienes
  • Cyclobutenes
  • Diels-Alder cycloaddition
  • Thermal ring-opening

ASJC Scopus subject areas

  • Organic Chemistry

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