Synthesis of diazirinyl photoprobe carrying a novel cleavable biotin

Jong Jip Park, Yutaka Sadakane, Katsuyoshi Masuda, Takenori Tomohiro, Taku Nakano, Yasumaru Hatanaka*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Rapid screening of receptor proteins is possible through the development of novel cleavable biotinylated photoaffinity probes that bear an acylsulfonamide linkage. The method purified photoaffinity biotinylated proteins by simple sequential steps without significant levels of contamination.

Original languageEnglish
Pages (from-to)814-818
Number of pages5
JournalChemBioChem
Volume6
Issue number5
DOIs
StatePublished - 2005/05

Keywords

  • Cleavable linkage
  • Cross-linking
  • Diazo compounds
  • Glycoconjugates
  • Photoaffinity labeling

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Synthesis of diazirinyl photoprobe carrying a novel cleavable biotin'. Together they form a unique fingerprint.

Cite this