Synthesis and properties of diazirinyl organo-platinum compounds for manipulations of photoaffinity labeled components

Makoto Hashimoto; Keitaro Furukawa; Takenori Tomohiro; Yasumaru Hatanaka

doi:10.1248/cpb.58.405

Synthesis and properties of diazirinyl organo-platinum compounds for manipulations of photoaffinity labeled components

Makoto Hashimoto^*, Keitaro Furukawa, Takenori Tomohiro, Yasumaru Hatanaka

^*Corresponding author for this work

Biorecognition Chemistry

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Synthesis of diazirinyl organo-platinum complexes, which specifically interact with purine base, characterization of photoreactivity and interaction between guanosine 5′-monophosphate (GMP) were examined. The results indicated that the diazirinyl organo-platinum complex was useful for manipulations of photoaffinity labeled components.

Original language	English
Pages (from-to)	405-407
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	58
Issue number	3
DOIs	https://doi.org/10.1248/cpb.58.405
State	Published - 2010/03

Keywords

Diazirine
Organo-platinum compound
Photoaffinity labeling

ASJC Scopus subject areas

General Chemistry
Drug Discovery

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10.1248/cpb.58.405

Cite this

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abstract = "Synthesis of diazirinyl organo-platinum complexes, which specifically interact with purine base, characterization of photoreactivity and interaction between guanosine 5′-monophosphate (GMP) were examined. The results indicated that the diazirinyl organo-platinum complex was useful for manipulations of photoaffinity labeled components.",

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AU - Hashimoto, Makoto

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AU - Tomohiro, Takenori

AU - Hatanaka, Yasumaru

PY - 2010/3

Y1 - 2010/3

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AB - Synthesis of diazirinyl organo-platinum complexes, which specifically interact with purine base, characterization of photoreactivity and interaction between guanosine 5′-monophosphate (GMP) were examined. The results indicated that the diazirinyl organo-platinum complex was useful for manipulations of photoaffinity labeled components.

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KW - Organo-platinum compound

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Synthesis and properties of diazirinyl organo-platinum compounds for manipulations of photoaffinity labeled components

Abstract

Keywords

ASJC Scopus subject areas

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