Striatal n-acetylaspartate synthetase Shati/Nat8l regulates depression-like behaviors via mGluR3-mediated serotonergic suppression in mice

Neuroscience

• Behavior (Neuroscience) 100%
• Serotonergic 100%
• Dorsal Striatum 100%
• N-Acetylaspartic Acid 100%
• Synthetase 100%
• Major Depressive Disorder 50%
• Metabotropic Glutamate Receptor 3 50%
• Glutamate Carboxypeptidase II 50%
• Serotonin 25%
• Metabolic Pathway 25%
• Social Interaction 25%
• Neurotransmitter 25%
• Tail Suspension Test 25%
• N-Acetyltransferase 25%
• Aspartic Acid 25%
• Adeno Associated Virus Vector 25%
• Behavioral Despair 25%
• Selective Serotonin Reuptake Inhibitor 25%
• Metabotropic Glutamate Receptor 2 25%
• Messenger RNA 25%
• Coenzyme A 25%

Keyphrases

• Depressive-like Behavior 100%
• Serotonergic 100%
• Shati 100%
• Striatal 100%
• MGluR3 100%
• Synthetase 100%
• N-acetylaspartate 41%
• Dorsal Striatum 33%
• N-acetylaspartylglutamate 25%
• Major Depressive Disorder 16%
• Forced Swimming 16%
• Metabotropic Glutamate Receptor 3 16%
• Glutamate Carboxypeptidase II (GCPII) 16%
• Metabolism 8%
• Psychiatric Disorders 8%
• Selective Serotonin Reuptake Inhibitors 8%
• Psychosis 8%
• MRNA Level 8%
• Human Brain 8%
• Neurotransmitters 8%
• Tail Suspension Test 8%
• Social Interaction Test 8%
• Acetyl Coenzyme A (acetyl-CoA) 8%
• Microinjection 8%
• Neurochemicals 8%
• Neuronal Network 8%
• Adeno-associated Viral Vector 8%
• N-acetyltransferase 2 (NAT2) 8%
• Behavioral Despair 8%
• Extracellular Space 8%
• Social Withdrawal 8%
• Serotonin Level 8%
• Functional Control 8%
• Metabotropic Glutamate Receptor 2/3 8%
• L-aspartate 8%