Stereoselective synthesis of the chiral tetrahydropyrane core of swinholides and misakinolides

Hiroyuki Hayakawa, Kouki Iida, Masahiro Miyazawa, Masaaki Miyashita*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Stereoselective synthesis of the optically pure tetrahydropyrane core of swinholides and misakinolide A starting from (S)-methyl lactate is described in which the highly stereoselective intramolecular iodoetherification for construction of the tetrahydropyrane ring and the regioselective ring-opening reaction of an epoxide are involved as key steps.

Original languageEnglish
Pages (from-to)601-602
Number of pages2
JournalChemistry Letters
Issue number7
DOIs
StatePublished - 1999

ASJC Scopus subject areas

  • General Chemistry

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