Stereoselective synthesis of steroid side chain and CD-rings. A route to (±)-de-ab-cholesta-8(14),22-dien-9-one

Takashi Takahashi*, Hiroaki Ueno, Masahiro Miyazawa, Jiro Tsuji

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

The stereoselective synthesis of (±)-de-AB-cholesta-8(14),22-dien-9-one from(±)-erythro-6-benzyloxy-5-hydroxy-8-methyl-l-tetrahydropyranyloxy-3(Z)-nonene by two Claisen rearrangements as a precursor of vitamin D3 is presented.

Original languageEnglish
Pages (from-to)4463-4466
Number of pages4
JournalTetrahedron Letters
Volume26
Issue number37
DOIs
StatePublished - 1985

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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