Reversible photoregulation of helical structures in short peptides under indoor lighting/dark conditions

Kazuhisa Fujimoto; Miwo Amano; Yohei Horibe; Masahiko Inouye

doi:10.1021/ol0526524

Reversible photoregulation of helical structures in short peptides under indoor lighting/dark conditions

Kazuhisa Fujimoto^*, Miwo Amano, Yohei Horibe, Masahiko Inouye

^*Corresponding author for this work

Member of the Board

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

A photochromic cross-linking agent with a spiropyran skeleton was developed for the reversible photoregulation of helical structures in short peptides. The helical contents of the cross-linked peptides could be regulated by ambient light and dark conditions at room temperature. This switching of the helical contents could be repeated several times without substantial loss of any activity.

Original language	English
Pages (from-to)	285-287
Number of pages	3
Journal	Organic Letters
Volume	8
Issue number	2
DOIs	https://doi.org/10.1021/ol0526524
State	Published - 2006/01/19

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol0526524

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title = "Reversible photoregulation of helical structures in short peptides under indoor lighting/dark conditions",

abstract = "A photochromic cross-linking agent with a spiropyran skeleton was developed for the reversible photoregulation of helical structures in short peptides. The helical contents of the cross-linked peptides could be regulated by ambient light and dark conditions at room temperature. This switching of the helical contents could be repeated several times without substantial loss of any activity.",

author = "Kazuhisa Fujimoto and Miwo Amano and Yohei Horibe and Masahiko Inouye",

year = "2006",

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doi = "10.1021/ol0526524",

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journal = "Organic Letters",

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T1 - Reversible photoregulation of helical structures in short peptides under indoor lighting/dark conditions

AU - Fujimoto, Kazuhisa

AU - Amano, Miwo

AU - Horibe, Yohei

AU - Inouye, Masahiko

PY - 2006/1/19

Y1 - 2006/1/19

N2 - A photochromic cross-linking agent with a spiropyran skeleton was developed for the reversible photoregulation of helical structures in short peptides. The helical contents of the cross-linked peptides could be regulated by ambient light and dark conditions at room temperature. This switching of the helical contents could be repeated several times without substantial loss of any activity.

AB - A photochromic cross-linking agent with a spiropyran skeleton was developed for the reversible photoregulation of helical structures in short peptides. The helical contents of the cross-linked peptides could be regulated by ambient light and dark conditions at room temperature. This switching of the helical contents could be repeated several times without substantial loss of any activity.

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U2 - 10.1021/ol0526524

DO - 10.1021/ol0526524

M3 - 学術論文

C2 - 16408896

AN - SCOPUS:31544482648

SN - 1523-7060

VL - 8

SP - 285

EP - 287

JO - Organic Letters

JF - Organic Letters

IS - 2

ER -

Reversible photoregulation of helical structures in short peptides under indoor lighting/dark conditions

Abstract

ASJC Scopus subject areas

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